Bertossi Dario, Nocini Riccardo, van der Lei Berend, Magistretti Philippe, Gualdi Alessandro, Pirayesh Ali, Marchetti Alberto
Department of Oral and Maxillofacial Surgery, University of Verona, Policlinico G.B. Rossi, Verona, Italy.
Section of Ear Nose and Throat (ENT), Department of Surgical Sciences, Dentistry, Gynecology and Pediatrics, University of Verona, Verona, Italy.
Plast Reconstr Surg Glob Open. 2021 Nov 24;9(11):e3957. doi: 10.1097/GOX.0000000000003957. eCollection 2021 Nov.
Aesthetic improvement of the lips with hyaluronic acid fillers is a popular procedure. A comprehensive, modular, and highly individualizable method has been developed: the Lip Omnicomprehensive Volume Enhancement (LOVE) approach. The present study assessed the safety and effectiveness of LOVE across different patient age groups.
This was a prospective, single-center study of women aged 20-70 years seeking nonsurgical lip enhancement or asymmetry correction. Three equally sized groups were formed based on patient age: 20-34, 35-45, and 46 years or older. Individualized treatment plans were developed taking into account patient preferences expressed in a pre-injection questionnaire. Treatment used one or more of the three modules of LOVE: lip shape [vermilion border, Vycross (VYC)-17.5]; volume (vermilion body, VYC-17.5); and hydration (submucosal area, VYC-12). Follow-up lasted 6 months.
Sixty patients were enrolled (mean age: 41.3 ± 13.3 years; n = 20 per age group), all of whom were White. Most were treated with all three LOVE modules. Mean filler quantities increased with age: 20-34 years, 1.1 ± 0.1 mL; 35-45 years, 1.5 ± 0.1 mL; 46 years or older, 1.6 mL ± 0.2 mL. Mean patient satisfaction at 4 weeks [on a seven-point scale from 0 (extremely dissatisfied) to 6 (extremely satisfied)] was 4.8-4.9 in each age group. Apart from minor and transient edema/bruising, there was only one complication: a case of lumps that resolved with home massage.
The LOVE approach is safe and effective across a range of ages, with high levels of patient satisfaction.
使用透明质酸填充剂改善唇部美观是一种常见的手术。已开发出一种全面、模块化且高度个性化的方法:唇部全方位容积增强(LOVE)方法。本研究评估了LOVE方法在不同年龄组患者中的安全性和有效性。
这是一项针对年龄在20 - 70岁之间寻求非手术唇部丰满或不对称矫正的女性的前瞻性单中心研究。根据患者年龄分为三个规模相等的组:20 - 34岁、35 - 45岁和46岁及以上。根据注射前问卷中表达的患者偏好制定个性化治疗方案。治疗使用LOVE的三个模块中的一个或多个:唇形[唇红缘,Vycross(VYC)-17.5];容积(唇红体,VYC-17.5);以及保湿(黏膜下区域,VYC-12)。随访持续6个月。
共纳入60例患者(平均年龄:41.3±13.3岁;每个年龄组n = 20),均为白人。大多数患者接受了所有三个LOVE模块的治疗。平均填充剂用量随年龄增加:20 - 34岁,1.1±0.1 mL;35 - 45岁,1.5±0.1 mL;46岁及以上,1.6 mL±(0.2 mL)。各年龄组患者在4周时的平均满意度[采用从0(极度不满意)到6(极度满意)的七点量表]为4.8 - 4.9。除了轻微和短暂的水肿/瘀伤外,仅出现一例并发症:一例肿块通过家庭按摩得以消退。
LOVE方法在各年龄段均安全有效,患者满意度高。