Shanghai Key Laboratory of Craniomaxillofacial Development and Diseases, Fudan University, Shanghai, China.
Department of Oral and Maxillofacial Surgery, Shanghai Stomatological Hospital, Fudan University, Shanghai, China.
J Int Med Res. 2021 Nov;49(11):3000605211060175. doi: 10.1177/03000605211060175.
Caries risk assessment tools are essential for identifying and providing treatment for individuals at high risk of developing caries. We aimed to develop a nomogram for the assessment and evaluation of caries risk among Chinese children.
We enrolled schoolchildren age 7 years from a primary school in Shanghai. Baseline information of participants was collected using a questionnaire completed by children's caregivers. A nomogram of a novel prediction scoring model was established based on predictors detected in univariate and multivariate analyses. Predictive accuracy and discriminative ability of the nomogram were calculated using the concordance index (C index). The bootstrap method (1000 samples) was used to decrease overfitting. The net benefit of the model was validated using decision curve analysis.
Overall, 406 children with complete information and two completed dental examinations were included in the final analysis. The nomogram based on logistic regression model coefficients demonstrated a C index of 0.766 (95% confidence interval: 0.761-0.771) for caries risk. The net benefit of the decision curve analysis was 38.6% at 55% threshold probability.
This nomogram model, derived using dietary habits, oral hygiene status, and caries experience, showed promising predictive ability to assess the caries risk among Chinese children.
龋病风险评估工具对于识别和治疗高龋风险个体至关重要。本研究旨在为中国儿童龋病风险评估和评价制定列线图。
我们招募了来自上海一所小学的 7 岁学龄儿童。通过儿童看护者填写的问卷收集参与者的基线信息。基于单变量和多变量分析中检测到的预测因子,建立了一种新的预测评分模型的列线图。使用一致性指数(C 指数)计算列线图的预测准确性和判别能力。采用 bootstrap 方法(1000 个样本)减少过拟合。使用决策曲线分析验证模型的净获益。
总体而言,406 名具有完整信息且完成两次口腔检查的儿童被纳入最终分析。基于逻辑回归模型系数的列线图显示,龋病风险的 C 指数为 0.766(95%置信区间:0.761-0.771)。决策曲线分析的净获益在 55%阈值概率时为 38.6%。
该列线图模型基于饮食习惯、口腔卫生状况和龋齿患病情况,具有良好的预测能力,可用于评估中国儿童的龋病风险。