早产儿视网膜病变：巴西巴拉那州两家新生儿重症监护病房发病的危险因素。
Retinopathy of prematurity: risk factors for its development in two neonatal intensive care units in Paraná-Brazil.
机构信息
Hospital Universitário Mackenzie de Curitiba, PR, Brazil.
Hospital de Olhos do Paraná, Curitiba, PR, Brazil.
出版信息
Arq Bras Oftalmol. 2021 Nov 29;85(4):364-369. doi: 10.5935/0004-2749.20220049. eCollection 2021.
PURPOSE
Evaluate the patients in two neonatal intensive care units in Paraná/Brazil and identify the risk factors for the development of retinopathy of prematurity.
METHODS
We performed a prospective cohort study on premature infants with gestational age ≤32 wk and/or with birth weight ≤1500 g who were admitted to the neonatal intensive care unit of Hospital do Trabalhador and Hospital Infantil Waldemar Monastier. These hospitals admit patients referred from other maternity hospitals in the state of Paraná. The study duration was 12 mon.
RESULTS
The incidence of retinopathy of prematurity was higher in the Hospital Infantil Waldemar Monastier than in the Hospital do Trabalhador for premature infants who needed to be transported from their birthplace to the intensive care unit (52.2% vs. 29.6%). The following risk factors were associated with the development of the disease: longer hospitalization, low gestational age at birth, longer oxygen use, vasoactive drugs use, no antenatal corticosteroids use, intracranial hemorrhage, and any glycemic disorder. Low birth weight was an independent risk factor for the development of retinopathy of prematurity.
CONCLUSION
Early neonatal care and transportation of premature infants may influence the occurrence and prognosis of retinopathy of prematurity.
目的
评估巴西南里奥格兰德州两家新生儿重症监护病房的患者，并确定发生早产儿视网膜病变的风险因素。
方法
我们对胎龄≤32 周和/或出生体重≤1500g 的早产儿进行了一项前瞻性队列研究，这些早产儿被收入 Trabalhador 医院和 Waldemar Monastier 儿童医院的新生儿重症监护病房。这两家医院接收的都是来自巴西南里奥格兰德州其他妇产医院转来的患者。研究持续时间为 12 个月。
结果
与需要从出生地转运到重症监护病房的早产儿相比，Waldemar Monastier 儿童医院早产儿视网膜病变的发生率高于 Trabalhador 医院（52.2% vs. 29.6%）。以下风险因素与疾病的发生有关：住院时间延长、出生时胎龄较低、氧疗时间延长、血管活性药物使用、未使用产前皮质激素、颅内出血和任何血糖紊乱。低出生体重是早产儿视网膜病变发生的独立危险因素。
结论
新生儿早期护理和早产儿转运可能会影响早产儿视网膜病变的发生和预后。
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