Al-Qahtani Bader, Al-Otaibi Mohammed, Alabdulajabbar Khaled, Selayem Nawaf Bin, Alshehri Waleed, Omair Aamir, Alsaif Saif
Department of Ophthalmology, College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.
Department of Neonatology, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia.
Middle East Afr J Ophthalmol. 2020 Jan 29;26(4):235-239. doi: 10.4103/meajo.MEAJO_131_18. eCollection 2019 Oct-Dec.
The purpose of the study was to determine the incidence of retinopathy of prematurity (ROP) in preterm infants in the neonatal intensive care unit (NICU), to identify the risk factors that predispose to ROP, and to assess the outcome of these infants.
This was a retrospective cohort study on premature infants with a birth weight (BW) of <1501 g or gestational age (GA) of <32 weeks. These infants were admitted to the NICU at a tertiary hospital in Riyadh, Saudi Arabia, from January 2010 to December 2014.
Five hundred and ninety-three infants were included; data were available for 581 infants. Of them, 224 infants (38.6%) had ROP. Of these, 22 infants (10.4%) had stage 3 ROP. The mean BW of infants with ROP was 938.4 ± 257.9 g, and the mean GA at birth was 27 ± 2.4 weeks. A significant relationship with a < 0.05 was found between the occurrence of ROP and small GA at birth, low BW, low APGAR score at 1 min, and long duration of receiving oxygen (O) therapy. Based on charts review, none of the infants had blindness.
The incidence of ROP in our study falls in the range of incidence in developing countries. The low BW and small GA were the most significant risk factors. Furthermore, it is also recommended to control the amount and duration of O therapy to as little as needed.
本研究的目的是确定新生儿重症监护病房（NICU）中早产儿视网膜病变（ROP）的发生率，识别易患ROP的危险因素，并评估这些婴儿的预后。
这是一项对出生体重（BW）<1501 g或胎龄（GA）<32周的早产儿进行的回顾性队列研究。这些婴儿于2010年1月至2014年12月在沙特阿拉伯利雅得的一家三级医院入住NICU。
共纳入593例婴儿；581例婴儿有可用数据。其中，224例婴儿（38.6%）患有ROP。其中，22例婴儿（10.4%）患有3期ROP。患有ROP的婴儿的平均BW为938.4±257.9 g，出生时的平均GA为27±2.4周。发现ROP的发生与出生时GA小、BW低、1分钟时APGAR评分低以及吸氧（O）治疗时间长之间存在显著关系（P<0.05）。根据病历审查，没有婴儿失明。
我们研究中ROP的发生率处于发展中国家的发生率范围内。低BW和小GA是最显著的危险因素。此外，还建议将O治疗的量和持续时间控制在所需的最低限度。
