Anaerobic digestion (AD) is a biochemical process that converts waste organic matter into energy-rich biogas with methane as the main component. Addition of electric electro-conductive, such as that nanoparticles (NP), has been shown to improve biogas generation. Interspecies electron transfer and direct interspecies electron transfer (DIET) using conductive materials is one of the mechanisms responsible for observed increases in CH. This article discusses the effect of the type and size of electro-conductive NPs on improving microbial degradation within AD systems, as well as the effect of electro-conductive NPs on microbial community shifts and syntrophic metabolism. Limitations and future perspectives of using NPs in an AD system is also discussed.