Lanni N, Scaglione B
Minerva Med. 1986 Mar 10;77(9-10):317-9.
20 patients suffering from severe lower respiratory tract infections were included in the study. 10 patients were given ceftriaxone (1-2 g/day) and the other 10 cefotaxime (2-4 g/day) for a week. The results of microbiological findings and both local and systemic tolerance were found to be similar for both drugs. This indicates that 7-14 g of ceftriaxone and 14-28 g of cefotaxime are equivalent quantities in the treatment of severe respiratory tract infections.
20名患有严重下呼吸道感染的患者被纳入该研究。10名患者接受头孢曲松(1 - 2克/天)治疗,另外10名患者接受头孢噻肟(2 - 4克/天)治疗,为期一周。发现两种药物的微生物学检查结果以及局部和全身耐受性均相似。这表明在治疗严重呼吸道感染时,7 - 14克头孢曲松和14 - 28克头孢噻肟的疗效相当。