Stomper P C, Jochelson M S, Friedman E L, Garnick M B, Richie J P
AJR Am J Roentgenol. 1986 Apr;146(4):745-8. doi: 10.2214/ajr.146.4.745.
The serial CT characteristics of nodal metastases from pure seminoma treated with chemotherapy were evaluated in 18 patients. Fifty percent of masses at presentation contained areas of low attenuation; none had calcification. After chemotherapy, masses completely resolved in four patients, partially resolved in 12 patients, and remained unchanged in one patient. The remaining patient developed progressive liver metastases during therapy and died. Pathologic evaluation of residual masses in four patients demonstrated only fibrosis. Residual masses in nine other patients demonstrated further partial resolution or remained stable over the following year; two developed calcification. These patients exhibited no clinical evidence of disease for a median follow-up of 22 or more months. Persistent but stable or resolving masses are common after chemotherapy for advanced seminoma. Unlike their nonseminomatous counterparts, they most often represent fibrosis in patients with no other clinical evidence of disease and do not warrant surgical excision.
对18例接受化疗的纯精原细胞瘤淋巴结转移的系列CT特征进行了评估。初诊时50%的肿块包含低密度区域；均无钙化。化疗后，4例患者的肿块完全消退，12例部分消退，1例无变化。其余1例患者在治疗期间出现进行性肝转移并死亡。对4例患者残留肿块的病理评估仅显示纤维化。其他9例患者的残留肿块在接下来的一年中进一步部分消退或保持稳定；2例出现钙化。这些患者在中位随访22个月或更长时间后无疾病的临床证据。晚期精原细胞瘤化疗后持续存在但稳定或消退的肿块很常见。与非精原细胞瘤不同，在没有其他疾病临床证据的患者中，它们最常代表纤维化，无需手术切除。
