阿拉伯世界的结直肠癌：一项系统综述。

Colorectal cancer in Arab world: A systematic review.

作者信息

Makhlouf Nahed A, Abdel-Gawad Muhammad, Mahros Aya M, Lashen Sameh A, Zaghloul Mariam, Eliwa Ahmed, Elshemy Eman E, Ali-Eldin Zainab, Abdeltawab Doaa, El-Raey Fathiya, Omran Dalia, Khalaf Marwa, Fanous Nancy, Abdelmohsen Ahmed Shawkat, Abu-Elfatth Ahmed, Abdelghani Mohamed, Farouk Mahmoud, Abdelaziz Mohamed, Alboraie Mohamed

机构信息

Department of Tropical Medicine and Gastroenterology, Faculty of Medicine, Assiut University, Assiut 71515, Egypt.

Department of Hepatology, Gastroenterology, and Infectious Diseases, Al-Azhar University, Assiut 71631, Egypt.

出版信息

World J Gastrointest Oncol. 2021 Nov 15;13(11):1791-1798. doi: 10.4251/wjgo.v13.i11.1791.

DOI:10.4251/wjgo.v13.i11.1791

PMID:34853651

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8603455/

Abstract

BACKGROUND

The incidence of colorectal cancer (CRC) is increasing among young individuals in the Arab world as well as in other regions of the world.

AIM

To explore the incidence and prevalence of CRC in the Arab world.

METHODS

The PubMed, Scopus, Web of Science, EBSCO and Wiley databases were searched to retrieve relevant articles irrespective of the language or the publication year. The search terms were "("colon OR rectum OR sigmoid OR rectal OR colonic OR colorectal") AND ("cancer OR malignancy OR malignant OR neoplasm") AND ("Jordan" OR "United Arab Emirates" OR "Bahrain" OR "Tunisia" OR "Algeria" OR "Djibouti" OR "Saudi Arabia" OR "Sudan" OR "Syria" OR "Somalia" OR "Iraq" OR "Oman" OR "Palestine" OR "Qatar" OR "Comoros" OR "Kuwait" OR "Lebanon" OR "Libya" OR "Egypt" OR "Morocco" OR "Mauritania" OR "Yemen"). Reviews, meta-analyses, and articles containing nonoriginal data were excluded. Retrieved articles were screened, and relevant data were extracted. Descriptive statistics were used for data analysis.

RESULTS

Nine studies were included. Five of the studies provided information regarding the prevalence of CRC. The prevalence of CRC was 0.72% in Saudi Arabia and 0.78% in the United Arab Emirate, while in Egypt, it ranged from 0.4% to 14%. Four studies showed information regarding the incidence. The annual incidence rate of CRC in Qatar was 7.5/100000/year. In Egypt, the crude incidence rate (CIR) in males was 3.1 for colon cancer and 1 for rectal cancer, while in females, it was 2.3 for colon cancer and 0.8 for rectal cancer. The age-standardized rate for CRC incidence in 2003 was 36.90 for males, 26.50 for females, and 30.49 for both sexes in Saudi Arabia. In 2016, the CIRs in Saudi Arabia were 3.6 and 2.1 in females for colon cancer and rectal cancer, respectively, while in males, it was 3.3 and 2.8 for colon cancer and rectal cancer, respectively. One study in Egypt revealed that 25% of CRC cases occurred among individuals younger than 40 years old.

CONCLUSION

There is a considerable prevalence of CRC in some Arab countries. More studies are needed to explore the incidence and prevalence of CRC in the rest of the Arab world.

摘要

背景

在阿拉伯世界以及世界其他地区，结直肠癌（CRC）在年轻人中的发病率正在上升。

目的

探讨阿拉伯世界结直肠癌的发病率和患病率。

方法

检索PubMed、Scopus、Web of Science、EBSCO和Wiley数据库，以检索相关文章，不考虑语言或出版年份。检索词为“（结肠或直肠或乙状结肠或直肠或结肠或结直肠）”且“（癌症或恶性肿瘤或恶性或肿瘤）”且“（约旦或阿拉伯联合酋长国或巴林或突尼斯或阿尔及利亚或吉布提或沙特阿拉伯或苏丹或叙利亚或索马里或伊拉克或阿曼或巴勒斯坦或卡塔尔或科摩罗或科威特或黎巴嫩或利比亚或埃及或摩洛哥或毛里塔尼亚或也门）”。排除综述、荟萃分析以及包含非原始数据的文章。对检索到的文章进行筛选，并提取相关数据。采用描述性统计进行数据分析。

结果

纳入9项研究。其中5项研究提供了结直肠癌患病率的信息。沙特阿拉伯的结直肠癌患病率为0.72%，阿拉伯联合酋长国为0.78%，而在埃及，患病率在0.4%至14%之间。4项研究显示了发病率的信息。卡塔尔的结直肠癌年发病率为7.5/10万/年。在埃及，男性结肠癌的粗发病率（CIR）为3.1，直肠癌为1；而女性结肠癌为2.3，直肠癌为0.8。2003年沙特阿拉伯结直肠癌发病率的年龄标准化率男性为36.90，女性为26.50，两性合计为30.49。2016年，沙特阿拉伯女性结肠癌和直肠癌的CIR分别为3.6和2.1，而男性结肠癌和直肠癌分别为3.3和2.8。埃及的一项研究表明，25%的结直肠癌病例发生在40岁以下的人群中。