Shouki Bazarbashi, Abdelsalam Alnajjar, Abdullah Al Sharm, Kanan Alshammari, Ahmed Al Sherhi, Emad Dawoud, Volker Heinemann, Mohamed Aseafan, Aref Chehal, Mohammed Alghamdi, Dina Hamza, Maroun Khoury, Ajit Venniyoor, Mervat Mahrous, Kakil Rasul, Shereef Elsamany, Diaeddine Trad
King Faisal Specialist Hospital & Research Center, Riyadh, Kingdom of Saudi Arabia.
Kuwait Cancer Control Center, Kuwait City, Kuwait.
Ther Adv Med Oncol. 2025 Jan 3;17:17588359241299324. doi: 10.1177/17588359241299324. eCollection 2025.
Colorectal cancer (CRC) represents a major public health challenge globally, particularly in the Gulf Cooperation Council (GCC) countries, where it is identified as the second most prevalent form of cancer. Despite advancements in management strategies, tailored guidelines specific to the Gulf region are lacking. This paper presents consensus recommendations developed by a panel of experts from the GCC countries to address this gap. The guidelines cover epidemiology, screening, biomarkers, and treatment strategies for metastatic CRC. Treatment guidelines emphasize tailored approaches based on tumor characteristics, including sidedness and molecular profiles. Furthermore, the importance of maintenance therapy and emerging biomarkers are discussed. These guidelines aim to improve CRC management and outcomes in the Gulf region.
结直肠癌（CRC）是全球主要的公共卫生挑战，在海湾合作委员会（GCC）国家尤为如此，在这些国家它被确定为第二大常见癌症形式。尽管管理策略有所进步，但缺乏针对海湾地区的定制指南。本文介绍了由海湾合作委员会国家的专家小组制定的共识性建议，以填补这一空白。这些指南涵盖了转移性结直肠癌的流行病学、筛查、生物标志物和治疗策略。治疗指南强调基于肿瘤特征的定制方法，包括肿瘤部位和分子特征。此外，还讨论了维持治疗的重要性和新兴生物标志物。这些指南旨在改善海湾地区结直肠癌的管理和治疗效果。
