Swinnen Bart E K S, de Bie Rob M A, van Rootselaar A F
Amsterdam UMC locatie AMC, afd. Neurologie en Klinische Neurofysiologie, Amsterdam.
Contact: Bart E.K.S. Swinnen (
Ned Tijdschr Geneeskd. 2021 Sep 30;165:D5777.
Orthostatic tremor is a rare disease characterized by difficulty with standing still. Patients often undergo a long diagnostic search and often feel underrecognized, partly due to unfamiliarity of physicians with the disease.
We report a 72-year-old male experiencing difficulty in standing still, accompanied by a tingling, trembling and painful sensation in the legs, over the last ten years. Several orthopedic and neurological causes had been suspected until neurological examination revealed a 'helicopter sign' upon auscultation of the leg muscles. Tremor registration showed a 14 Hz tremor in the legs upon standing, confirming the diagnosis of orthostatic tremor. There was moderate improvement with pharmacological treatment.
Orthostatic tremor should be suspected in patients with instability or atypical symptoms upon standing. A neurological referral including tremor registration is recommended in these cases.
直立性震颤是一种罕见疾病,其特征为难以保持静止站立。患者通常要经过漫长的诊断过程,且常感觉未得到充分认识,部分原因是医生对该疾病不熟悉。
我们报告一名72岁男性,在过去十年中一直存在难以静止站立的问题,并伴有腿部刺痛、颤抖和疼痛的感觉。在神经科检查发现腿部肌肉听诊时有“直升机征”之前,曾怀疑过多种骨科和神经科病因。震颤记录显示站立时腿部有14赫兹的震颤,从而确诊为直立性震颤。药物治疗后有中度改善。
对于站立时出现不稳或非典型症状的患者,应怀疑直立性震颤。在这些病例中,建议转诊至神经科并进行震颤记录。