Quadackers Davy M C, Cath Danielle C, Liemburg Edith J, Houtman Ingrid E M, Oud Marian J T, Berger Marjolein Y, Cahn Wiepke, Mulder Hans
UMC Groningen, Rob Giel Onderzoekcentrum,Groningen.
Contact: Davy M.C. Quadackers (
Ned Tijdschr Geneeskd. 2021 Oct 28;165:D5747.
Psychiatric conditions are insufficiently highlighted as cardiovascular risk factors in the CVRM guideline. Objectives of this review are 1) to determine if anxiety and mood symptoms/disorders are independent cardiovascular risk factors; 2) to compare this risk to a population without these psychiatric conditions and 3) to ascertain the influence of psychiatric disease severity.
Narrative systematic review METHOD: We searched for meta-analyses and systematic reviews in PubMed. Quality assessment by AMSTAR criteria.
10 reviews were included from 172 hits. (Sub)clinical depression and mood disorders are associated with an increased independent risk to develop cardiovascular diseases, coronary artery disease, myocardial infarction and cerebrovascular disease. Bipolar disorders increase the cerebrovascular risk, but not myocardial infarction. Anxiety disorders/symptoms heighten the cardiovascular, myocardial and cerebrovascular risk.
Anxiety and mood symptoms/disorders are independent cardiovascular risk factors. Severe anxiety and mood disorders should be included as separate risk factors in the CVRM guideline.
在心血管风险管理(CVRM)指南中,精神疾病作为心血管危险因素未得到充分重视。本综述的目的是:1)确定焦虑和情绪症状/障碍是否为独立的心血管危险因素;2)将此风险与无这些精神疾病的人群进行比较;3)确定精神疾病严重程度的影响。
叙述性系统综述
我们在PubMed中检索了荟萃分析和系统综述。采用AMSTAR标准进行质量评估。
从172条检索结果中纳入了10篇综述。(亚)临床抑郁和情绪障碍与发生心血管疾病、冠状动脉疾病、心肌梗死和脑血管疾病的独立风险增加相关。双相情感障碍增加脑血管疾病风险,但不增加心肌梗死风险。焦虑症/症状会增加心血管、心肌和脑血管疾病风险。
焦虑和情绪症状/障碍是独立的心血管危险因素。严重焦虑和情绪障碍应作为单独的危险因素纳入CVRM指南。