Department of Medicine, Faculty of Clinical Sciences, College of Medicine, University of Lagos/ Lagos University Teaching Hospital (LUTH), Idi-Araba, Lagos State, Nigeria.
Department of Medicine, Faculty of Clinical Sciences, University of Port Harcourt Teaching Hospital, Port Harcourt, Rivers State, Nigeria.
West Afr J Med. 2021 Oct 29;Vol. 38(10):944-951.
Cutaneous manifestations of COVID-19 have been documented from Europe, USA, and China but none from Africa to date. Skin findings among Africans differ from Caucasians and it is important to report these in Nigerians with COVID-19.
A prospective observational review involving patients seen at the Emergency triage, and Isolation wards of the Lagos University Teaching Hospital. Demographic and clinical data were captured; skin and appendages were examined by a dermatologist between 0800hrs and 1600hours to minimise visual errors of artificial light masking cutaneous lesions.
Of 235 participants, 17 (7.23%) had recent onset skin rash, with 7 (41.2%) experienced itching and 11 confirmed with COVID-19. There was a male: female ratio of 97:43 (2.3:1) among COVID-19 patients. Cutaneous findings were seen in 12 (5.1%) participants, with the face and trunk mostly affected and acne plus papular eruptions predominating. There was no significant relationship between COVID-19 and recent onset skin rash (χ2, p = 0.87). Only 2 of the 17 participants had a previously existing dermatoses ((χ2, p = 0.84). There was no significant relation between use of medications and onset of rashes (χ2, p = 0.72) or between those with co-morbidities and onset of rashes (χ2, p = 0.51).
Cutaneous manifestations were found among Nigerian patients with SARS-CoV-2 infection. Most presented with pruritus and papular eruptions and no morphologic pattern was demonstrated. Physicians and dermatologists need to be aware and look out for skin changes in SARS-CoV-2 infection as they may be early pointers to COVID-19. Keywords: Cutaneous findings, manifestations, Skin, COVID-19, Nigeria.
COVID-19 的皮肤表现已在欧洲、美国和中国得到记录，但迄今为止尚未在非洲发现。非洲人的皮肤表现与白种人不同，因此在报告尼日利亚的 COVID-19 患者时，报告这些皮肤表现很重要。
这是一项前瞻性观察性综述，涉及在拉各斯大学教学医院急诊分诊和隔离病房就诊的患者。记录了人口统计学和临床数据；皮肤科医生在上午 8 点至下午 4 点之间检查皮肤和附属物，以最大程度减少人工光掩盖皮肤病变的视觉误差。
在 235 名参与者中，有 17 名（7.23%）有近期新发皮疹，其中 7 名（41.2%）有瘙痒，11 名确诊为 COVID-19。COVID-19 患者中男女比例为 97:43（2.3:1）。在 12 名（5.1%）参与者中观察到皮肤表现，面部和躯干受影响最常见，粉刺和丘疹性皮疹为主。COVID-19 与近期新发皮疹之间无显著关系（χ2，p = 0.87）。在 17 名有近期新发皮疹的参与者中，仅有 2 名（χ2，p = 0.84）有先前存在的皮肤病。药物使用与皮疹发作之间无显著关系（χ2，p = 0.72），也与合并症与皮疹发作之间无显著关系（χ2，p = 0.51）。
在感染 SARS-CoV-2 的尼日利亚患者中发现了皮肤表现。大多数表现为瘙痒和丘疹性皮疹，没有显示出特定的形态模式。医生和皮肤科医生需要意识到并注意 SARS-CoV-2 感染中的皮肤变化，因为它们可能是 COVID-19 的早期指标。关键词：皮肤表现、皮肤表现、皮肤、COVID-19、尼日利亚。
