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2020 年 3 月至 8 月波多黎各因实验室确诊 COVID-19 住院患者的特征和临床结局。

Characteristics and clinical outcomes of patients hospitalized with laboratory-confirmed COVID-19-Puerto Rico, March-August 2020.

机构信息

U. S. Centers for Disease Control and Prevention, San Juan, Puerto Rico, United States of America.

Hospital Auxilio Mutuo and Adult's University Hospital, San Juan, Puerto Rico, United States of America.

出版信息

PLoS One. 2021 Dec 2;16(12):e0260599. doi: 10.1371/journal.pone.0260599. eCollection 2021.

Abstract

Hispanics are the majority ethnic population in Puerto Rico where we reviewed charts of 109 hospitalized COVID-19 patients to better understand demographic and clinical characteristics of COVID-19 and determine risk factors for poor outcomes. Eligible medical records of hospitalized patients with confirmed COVID-19 illnesses were reviewed at four participating hospitals in population centers across Puerto Rico and data were abstracted that described the clinical course, interventions, and outcomes. We found hospitalized patients had a median of 3 underlying conditions with obesity and diabetes as the most frequently reported conditions. Intensive care unit (ICU) admission occurred among 28% of patients and 18% of patients died during the hospitalization. Patients 65 or older or with immune deficiencies had a higher risk for death. Common symptoms included cough, dyspnea, and fatigue; less than half of patients in the study reported fever which was less frequent than reported elsewhere in the literature. It is important for interventions within Hispanic communities to protect high-risk groups.

摘要

波多黎各的主要族裔群体是西班牙裔,我们在此回顾了 109 名住院 COVID-19 患者的图表,以更好地了解 COVID-19 的人口统计学和临床特征,并确定不良结局的危险因素。在波多黎各四个人口中心的参与医院回顾了符合 COVID-19 疾病住院条件的合格病历,并提取了描述临床过程、干预措施和结果的数据。我们发现住院患者平均有 3 种基础疾病,肥胖症和糖尿病是最常报告的疾病。28%的患者入住重症监护病房(ICU),18%的患者在住院期间死亡。65 岁或以上或有免疫缺陷的患者死亡风险更高。常见症状包括咳嗽、呼吸困难和疲劳;研究中不到一半的患者报告有发热,这比文献中其他地方报告的频率要低。在西班牙裔社区内进行干预以保护高危人群非常重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0427/8638975/00404410294e/pone.0260599.g001.jpg

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