Medical Research and Careers Organisation, Bamenda, Northwest Region, Cameroon.
Manchester University NHS Foundation Trust, Greater Manchester, Manchester, United Kingdom.
PLoS One. 2021 Dec 2;16(12):e0260819. doi: 10.1371/journal.pone.0260819. eCollection 2021.
Studies assessing the mental health of patients with COVID-19 infection remain limited. Disasters and major emergencies, not just COVID-19, undoubtedly lead to greater incidence of mental health problems. Previous studies indicate that the novel Coronavirus disease can cause panic and stress in patients. Our literature search didn't reveal any previous published data from Cameroon and the Central African sub-region. In order to bridge this gap, we assessed the prevalence and factors associated with depression and anxiety in COVID-19 patients. We carried out a cross-sectional study in a secondary hospital in the Littoral Region of Cameroon. We recruited hospitalised COVID-19 patients during a 4-month period. We collected data on sociodemographic characteristics. The HADS score was used to assess levels of anxiety and depression. All analysis were done using Stata 14. A P value of <0.05 was used as the cut-off for statistical significance. A total number of 285 patients took part in this study with a mean age of 48.47 years. The prevalence of anxiety in COVID-19 patients was 60.35% while the prevalence of depression was 81.40%. At multivariate logistic regression male gender (OR: 1.89, P = 0.04), hypoxaemia (OR: 2.20, P = 0.01), presence of COVID-19 complications (OR: 1.61, P = 0.02) and current episode of depression (OR: 4.14, P<0.01) were independently associated with anxiety. Similarly, age > 35 years (OR:2.03, P = 0.02), presence of comorbidity (OR: 1.68, P = 0.01), BMI > = 30kg/m2 (OR: 1.78, P = 0.02), presence of COVID-19 complications (OR: 1.28, P = 0.01) and anxiety (OR: 4.60, P<0.001) were independently associated with depression. Hospitalised patients with COVID-19 experienced high levels of anxiety and depression. Treatment of hospitalised patients with COVID-19 should therefore include psychotherapy and psychiatric support.
评估 COVID-19 感染患者心理健康的研究仍然有限。灾难和重大紧急情况，不仅仅是 COVID-19，无疑会导致更多的心理健康问题。先前的研究表明，新型冠状病毒疾病会导致患者产生恐慌和压力。我们的文献检索没有发现来自喀麦隆和中非次区域的先前发表的数据。为了弥补这一空白，我们评估了 COVID-19 患者中抑郁和焦虑的患病率和相关因素。我们在喀麦隆滨海地区的一家二级医院进行了一项横断面研究。我们在 4 个月的时间内招募了住院的 COVID-19 患者。我们收集了社会人口学特征的数据。使用 HADS 评分评估焦虑和抑郁程度。所有分析均使用 Stata 14 进行。P 值<0.05 用作统计显著性的截止值。共有 285 名患者参加了这项研究，平均年龄为 48.47 岁。COVID-19 患者中焦虑的患病率为 60.35%，而抑郁的患病率为 81.40%。在多变量逻辑回归中，男性（OR：1.89，P=0.04）、低氧血症（OR：2.20，P=0.01）、COVID-19 并发症（OR：1.61，P=0.02）和当前抑郁发作（OR：4.14，P<0.01）与焦虑独立相关。同样，年龄>35 岁（OR：2.03，P=0.02）、合并症（OR：1.68，P=0.01）、BMI≥30kg/m2（OR：1.78，P=0.02）、COVID-19 并发症（OR：1.28，P=0.01）和焦虑（OR：4.60，P<0.001）与抑郁独立相关。住院 COVID-19 患者经历了高水平的焦虑和抑郁。因此，COVID-19 住院患者的治疗应包括心理治疗和精神支持。
