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皮肤孤立性非亲表皮性T细胞假性淋巴瘤

Solitary nonepidermotropic T cell pseudolymphoma of the skin.

作者信息

van der Putte S C, Toonstra J, Felten P C, van Vloten W A

出版信息

J Am Acad Dermatol. 1986 Mar;14(3):444-53. doi: 10.1016/s0190-9622(86)70055-8.

Abstract

A possibly new type of T cell pseudolymphoma is described in three cases. It presented as a small, solitary lesion on the trunk of 3 to 5 months' duration. It was slightly elevated, round, and erythematous, with a diameter of 1 to 2 cm. It showed a tendency to regress spontaneously. In sharp contrast to its benign clinical appearance and biologic behavior, a distinct malignant histopathologic picture was observed, however. It was characterized by a nonepidermotropic bandlike subepidermal infiltrate dominated by large T lymphocytes with cerebriform nuclei identical in morphologic and immunologic characteristics to the abnormal cellular component of cutaneous T-cell lymphomas.

摘要

本文描述了三例可能为新型的T细胞假性淋巴瘤。其表现为躯干上一个持续3至5个月的小的孤立性损害。损害略隆起,圆形,呈红斑状,直径1至2厘米。它有自发消退的倾向。然而,与其良性的临床外观和生物学行为形成鲜明对比的是,观察到了明显的恶性组织病理学表现。其特征为非亲表皮的带状表皮下浸润,以大T淋巴细胞为主,这些细胞具有脑回状核,在形态学和免疫学特征上与皮肤T细胞淋巴瘤的异常细胞成分相同。

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