Antibodies to collagen types I-VI in Dupuytren's contracture.
作者信息
Pereira R S, Black C M, Turner S M, Spencer J D
出版信息
J Hand Surg Br. 1986 Feb;11(1):58-60. doi: 10.1016/0266-7681(86)90014-8.
PMID:3485693
Abstract
Sera from 16 patients with Dupuytren's contracture were tested for IgG and IgM antibodies to native and denatured human collagen types I, II, III, IV, V and VI. IgG antibody to at least one collagen type was found in 11/16 (69%) of these patients, compared with 27/96 (28%) normal adult blood donor controls. The prevalence of antibody to denatured type II collagen was raised, and although there was no overall increase in HLA-DR4 compared with a control population, this antibody was associated with HLA-DR4 in this patient group.
摘要
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