Central Virology Laboratory, Ministry of Health, Ramat-Gan, Israel.
Department of Epidemiology and Preventive Medicine, School of Public Health, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Euro Surveill. 2021 Dec;26(48). doi: 10.2807/1560-7917.ES.2021.26.48.2101040.
Until recently, children and adolescents were not eligible for COVID-19 vaccination. They may have been a considerable source of SARS-CoV-2 spread. We evaluated SARS-CoV-2 IgG antibody seroprevalence in Israeli children aged 0-15 years from January 2020 to March 2021. Seropositivity was 1.8-5.5 times higher than COVID-19 incidence rates based on PCR testing. We found that SARS-CoV-2 infection among children is more prevalent than previously thought and emphasise the importance of seroprevalence studies to accurately estimate exposure.
直到最近，儿童和青少年都没有资格接种 COVID-19 疫苗。他们可能是 SARS-CoV-2 传播的一个重要来源。我们评估了 2020 年 1 月至 2021 年 3 月期间以色列 0-15 岁儿童的 SARS-CoV-2 IgG 抗体血清阳性率。血清阳性率比基于 PCR 检测的 COVID-19 发病率高 1.8-5.5 倍。我们发现，儿童中的 SARS-CoV-2 感染比之前认为的更为普遍，这强调了血清阳性率研究对于准确估计暴露的重要性。
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