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在 ACS-NSQIP 数据库中,由 5 项虚弱指数(5-iFI)预测的肾上腺切除术结局。

Adrenalectomy outcomes predicted by a 5-item frailty index (5-iFI) in the ACS-NSQIP database.

机构信息

Department of Urology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Department of Urology, Montefiore Medical Center and Albert Einstein College of Medicine, Bronx, NY, USA.

出版信息

Am J Surg. 2022 Jun;223(6):1120-1125. doi: 10.1016/j.amjsurg.2021.11.020. Epub 2021 Nov 26.

Abstract

BACKGROUND

Frailty has been shown to be a predictor of adverse postoperative outcomes. This study aims to evaluate a 5-item frailty index (5-iFI) as a predictor of complications as well as healthcare resource utilization (HCRU) following adrenalectomy.

METHODS

All adrenalectomy cases recorded in the ACS-NSQIP database from 2015 to 2018 were analyzed. Primary outcomes of interest were Clavien-Dindo [CD] I/II or CD IV complications and HCRU. HCRU outcomes were prolonged length of stay (PLOS), discharge to continued care (DCC), and unplanned 30-day readmission (UR).

RESULTS

4358 patients were included. Higher 5-iFI scores were associated with higher rates of CDI/II, CDIV, and increased HCRU (p < 0.05). On multivariate analysis, 5-iFI scores were found to be independent predictors of adverse clinical and HCRU outcomes.

CONCLUSIONS

Frailty tools like the 5i-FI can be useful in preoperative risk-benefit analysis, patient counseling, and planning prehabilitation interventions.

摘要

背景

虚弱已被证明是术后不良结局的预测因素。本研究旨在评估 5 项虚弱指数(5-iFI)作为肾上腺切除术术后并发症和医疗保健资源利用(HCRU)的预测指标。

方法

分析了 2015 年至 2018 年 ACS-NSQIP 数据库中记录的所有肾上腺切除术病例。主要观察指标为 Clavien-Dindo [CD] I/II 或 CD IV 并发症和 HCRU。HCRU 结果包括延长住院时间(PLOS)、转至持续护理(DCC)和计划外 30 天再入院(UR)。

结果

纳入 4358 例患者。较高的 5-iFI 评分与更高的 CDI/II、CDIV 发生率和增加的 HCRU 相关(p<0.05)。多变量分析显示,5-iFI 评分是不良临床和 HCRU 结局的独立预测指标。

结论

虚弱工具,如 5i-FI,可以在术前风险效益分析、患者咨询和计划康复干预中发挥作用。

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