Ruiz Department of Ophthalmology and Visual Science, McGovern Medical School at The University of Texas Health Science Center at Houston (UTHealth), Houston, TX, USA.
Memorial Hermann-Texas Medical Center, Houston, TX, USA.
Eye (Lond). 2022 Dec;36(12):2323-2327. doi: 10.1038/s41433-021-01869-4. Epub 2021 Dec 2.
To describe clinical characteristics and visual outcomes of non-traumatic open globe injuries.
A level 1 trauma centre in a large urban medical centre.
Retrospective study.
Charts of non-traumatic open globe patients admitted to MHH-TMC from 1/2010 to 3/2015 were reviewed for demographics, cause, clinical characteristics, visual acuity (VA) and enucleation.
Thirty eyes were included: 15 (50%) were males with a mean age of 47 (±28) years. All presented with zone 1 injury. Twenty-five (83%) had a perforated corneal ulcer. Presenting VA was count fingers (n = 3, 10%) to NLP (n = 6, 20%). Twenty-four (80%) involved infection, 5 (17%) congenital, 3 (10%) chemical burn and 2 (7%) neurotrophic. Conjunctival injection (n = 22, 77%), corneal opacification (n = 20, 71%) and relative afferent pupillary defect (n = 9, 44%) were common. After treatment, 23 (88%) were worse than 6/60 (20/200), 9 (35%) were NLP and 8 (27%) required enucleation.
Often non-traumatic open globe injuries are zone 1 and due to perforated infectious ulcers. Compared to previously reported traumatic injuries, these have higher rates of enucleation (27% vs 8%) and poorer final VA (88% vs 68% worse than 6/60 20/200).
描述非外伤性开放性眼球损伤的临床特征和视力结果。
大型城市医疗中心的 1 级创伤中心。
回顾性研究。
回顾 2010 年 1 月至 2015 年 3 月期间入住 MHH-TMC 的非外伤性开放性眼球损伤患者的病历，记录人口统计学、病因、临床特征、视力和眼球摘除情况。
纳入 30 只眼：15 只（50%）为男性，平均年龄 47（±28）岁。所有患者均为 1 区损伤。25 只（83%）有穿孔性角膜溃疡。就诊时视力为指数（n=3，10%）至无光感（n=6，20%）。24 只（80%）与感染有关，5 只（17%）为先天性，3 只（10%）为化学烧伤，2 只（7%）为神经源性。常见的有结膜充血（n=22，77%）、角膜混浊（n=20，71%）和相对性传入性瞳孔障碍（n=9，44%）。治疗后，23 只（88%）视力低于 6/60（20/200），9 只（35%）无光感，8 只（27%）需要眼球摘除。
非外伤性开放性眼球损伤通常为 1 区，且多由穿孔性感染性溃疡引起。与之前报道的外伤性损伤相比，这些损伤眼球摘除率更高（27% vs 8%），最终视力更差（88% vs 68%低于 6/60 20/200）。
