Doruyter Alexander G G, Parkes Jeannette, Carr Jonathan, Warwick James M
NuMeRI Node for Infection Imaging, Central Analytical Facilities, Stellenbosch University, Cape Town, South Africa.
Division of Nuclear Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.
SA J Radiol. 2021 Nov 10;25(1):2201. doi: 10.4102/sajr.v25i1.2201. eCollection 2021.
Positron emission tomography combined with X-ray computed tomography (PET-CT) has an established role in the management of brain disorders, but may be underutilised in South Africa. Possible barriers to access include the limited number of PET-CT facilities and the lack of contemporary guidelines for the use of brain PET-CT in South Africa. The current review aims to highlight the evidence-based usage of brain Positron emission tomography (PET) in dementia, movement disorders, brain tumours, epilepsy, neuropsychiatric lupus, immune-mediated encephalitides, and brain infections. While being areas of research, there is currently no clinical role for the use of PET-CT in traumatic brain injury or in psychiatric or neurodevelopmental disorders. Strategies to expand the appropriate use of PET-CT in brain disorders are discussed in this article.
正电子发射断层扫描与X射线计算机断层扫描相结合（PET-CT）在脑部疾病的管理中已确立了作用，但在南非可能未得到充分利用。获取PET-CT的可能障碍包括PET-CT设备数量有限，以及南非缺乏关于脑部PET-CT使用的当代指南。本综述旨在强调脑正电子发射断层扫描（PET）在痴呆、运动障碍、脑肿瘤、癫痫、神经精神性狼疮、免疫介导性脑炎和脑部感染中的循证应用。虽然PET-CT在创伤性脑损伤、精神疾病或神经发育障碍方面属于研究领域，但目前尚无临床应用价值。本文讨论了在脑部疾病中扩大PET-CT合理使用的策略。
