Department of Clinical Sciences, Faculty of Medicine, Lund University, Lund, Sweden.
Research and Development Center, Skaraborg Hospital, Skövde, Sweden.
Eur J Trauma Emerg Surg. 2022 Dec;48(6):4489-4497. doi: 10.1007/s00068-021-01842-6. Epub 2021 Dec 3.
To determine and compare the sensitivity, specificity, and proportion of patients eligible for discharge by the Brain Injury Guidelines and the Mild TBI Risk Score in patients with mild traumatic brain injury and concomitant intracranial injury.
Retrospective review of the medical records of adult patients with traumatic intracranial injuries and an initial Glasgow Coma Scale score of 14-15, who sought care at Helsingborg Hospital between 2014/01/01 and 2019/12/31. Both guidelines were theoretically applied. The sensitivity, specificity, and percentage of the cohort that theoretically could have been discharged by either guideline were calculated. The outcome was defined as death, in-hospital intervention, admission to the intensive care unit, requiring emergency intubation due to intracranial injury, decreased consciousness, or seizure within 30 days of presentation.
Of the 538 patients included, 8 (1.5%) and 10 (1.9%) were eligible for discharge according to the Brain Injury Guidelines and the Mild TBI Risk Score, respectively. Both guidelines had a sensitivity of 100%. The Brain Injury Guidelines had a specificity of 2.3% and the Mild TBI Risk Score had a specificity of 2.9%.
There was no difference between the two guidelines in sensitivity, specificity, or proportion of the cohort eligible for discharge. Specificity and proportion of cohort eligible for discharge were lower than each guideline's original study. At present, neither guideline can be recommended for implementation in the current or similar settings.
确定并比较脑损伤指南和轻度创伤性脑损伤风险评分在伴有颅内损伤的轻度创伤性脑损伤患者中对出院患者的灵敏度、特异性和比例。
回顾性分析了 2014 年 1 月 1 日至 2019 年 12 月 31 日在赫尔辛堡医院就诊的创伤性颅内损伤和初始格拉斯哥昏迷量表评分 14-15 的成年患者的病历。两种指南均进行理论应用。计算了两种指南理论上可出院的队列的灵敏度、特异性和百分比。结果定义为死亡、住院干预、入住重症监护病房、因颅内损伤需要紧急插管、意识下降或发病后 30 天内癫痫发作。
在纳入的 538 例患者中,根据脑损伤指南和轻度创伤性脑损伤风险评分,分别有 8 例(1.5%)和 10 例(1.9%)符合出院标准。两种指南的灵敏度均为 100%。脑损伤指南的特异性为 2.3%,轻度创伤性脑损伤风险评分的特异性为 2.9%。
两种指南在灵敏度、特异性或可出院患者队列比例方面没有差异。特异性和可出院患者队列的比例低于每个指南的原始研究。目前,两种指南都不能推荐在当前或类似环境中实施。