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腹腔镜袖状胃切除术前后的生活质量评估:一项前瞻性研究。

Quality of life assessment before and after laparoscopic sleeve gastrectomy: a prospective study.

作者信息

Mocian F, Coroș M

机构信息

Third Department of Surgery, "George Emil Palade" University of Medicine, Pharmacy, Science and Technology of Târgu Mureș, Târgu Mureș, Romania.

出版信息

Eur Rev Med Pharmacol Sci. 2021 Nov;25(22):6934-6940. doi: 10.26355/eurrev_202111_27242.

Abstract

OBJECTIVE

Obesity has a negative effect on the quality of life (QoL), and therefore, the goal of bariatric surgery is not only to decrease excess weight but also to improve QoL and obesity-related comorbidities. Laparoscopic sleeve gastrectomy (LSG) has become the most commonly applied bariatric procedure worldwide, although there is a lack of prospective data on QoL in patients undergoing this procedure. Therefore, this prospective study aimed to compare QoL of obese patients before, and one year after LSG, and also to analyze the weight loss process and resolution of obesity-related comorbidities.

PATIENTS AND METHODS

Patients undergoing LSG between January 2019 and December 2019 were included. They completed the Bariatric Quality of Life index (BQL) before surgery and one year after. Anthropometric data and obesity-related comorbidities were recorded.

RESULTS

Thirty-eight patients were included in the study. The mean age was 37.9 ± 11.2 years, and the majority were women (68.4%). One year after the surgery, the mean body mass index (BMI) decreased from 45.5 ± 8.2 kg/m2 to 29.3 ± 6.1 kg/m2 (p<0.0001), and the mean percentage excess weight loss (%EWL) was 85.1 ± 22.3%. The preoperative total score of BQL was 46.05 ± 7.01 points and postoperatively it increased to 66.52 ± 5.53 points (p<0.0001). BQL total score and %EWL was positively and significantly correlated (r=0.479, p=0.002). Postoperatively, all obesity-related comorbidities were improved, although de novo gastroesophageal reflux disease (GERD) appeared in 7.8% of the cases.

CONCLUSIONS

LSG improves QoL and allows resolution of obesity-related comorbidities, but a small proportion of patients may develop troublesome GERD postoperatively.

摘要

目的

肥胖对生活质量(QoL)有负面影响,因此,减肥手术的目标不仅是减轻超重,还要改善生活质量和与肥胖相关的合并症。腹腔镜袖状胃切除术(LSG)已成为全球最常用的减肥手术,尽管缺乏关于接受该手术患者生活质量的前瞻性数据。因此,这项前瞻性研究旨在比较肥胖患者在接受LSG手术前和术后一年的生活质量,并分析体重减轻过程以及与肥胖相关合并症的缓解情况。

患者与方法

纳入2019年1月至2019年12月期间接受LSG手术的患者。他们在手术前和术后一年完成了减肥生活质量指数(BQL)。记录人体测量数据和与肥胖相关的合并症。

结果

38名患者纳入研究。平均年龄为37.9±11.2岁,大多数为女性(68.4%)。手术后一年,平均体重指数(BMI)从45.5±8.2kg/m²降至29.3±6.1kg/m²(p<0.0001),平均超重减轻百分比(%EWL)为85.1±22.3%。术前BQL总分是46.05±7.01分,术后增至66.52±5.53分(p<0.0001)。BQL总分与%EWL呈显著正相关(r=0.479,p=0.002)。术后,所有与肥胖相关的合并症均得到改善,尽管7.8%的病例出现了新发胃食管反流病(GERD)。

结论

LSG可改善生活质量并使与肥胖相关的合并症得到缓解,但一小部分患者术后可能会出现麻烦的GERD。

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