Ayala Mariana, Marchant Margarita, Hertz Cristina, Castillo Gloria
Dialysis Centers NephroCare Chile, Fresenius Medical Care, Duble Almeyda 2915, 7790569, Ñuñoa, Santiago, Chile.
Int Urol Nephrol. 2022 Aug;54(8):1947-1955. doi: 10.1007/s11255-021-03077-1. Epub 2021 Dec 3.
The study assessed the impact of intradialytic oral nutritional supplementation on the quality of life in patients receiving hemodialysis and diagnosed with protein energy wasting.
A pre-test post-test quasi-experimental study was conducted before and after 3 months of intradialytic oral nutritional supplementation on 109 older hemodialysis patients. We measured before and after 3 months of intradialytic oral nutritional supplementation, the quality of life score, the burden of kidney disease, three quality of life scales and the mental and physical health status using KDQoL-SF™ 1.3, body composition and biochemical parameters of nutritional condition.
The mean age of the patients was 69.4 ± 3.4 years, 59% were male, and the time on dialysis was 63.5 ± 52.6 months. Comparing the baseline with month 3 of intradialytic oral nutritional supplementation, we observed to better quality of life. In contrast to malnutrition, score, specifically increased significantly score of symptoms/problems list related to hemodialysis, sexual function, social and cognitive function, sleep, pain, energy/fatigue and general state of health. Significant changes were also found in nutritional status, energy intake and body composition indicators. After 3 months of intradialytic oral nutritional supplementation, we observed a nutritional status recovery in one or more indicators in 92% of the patients.
Our findings indicate that 3 months of intradialysis oral nutritional supplementation improves the components of physical and mental quality of life and nutritional status in older patients receiving hemodialysis diagnosed with loss of protein energy. These results are relevant to improve the experience of patients with protein energy loss receiving hemodialysis.
本研究评估了透析期间口服营养补充对接受血液透析且被诊断为蛋白质能量消耗的患者生活质量的影响。
对109例老年血液透析患者进行了一项前后测准实验研究，在透析期间口服营养补充3个月前后进行。我们在透析期间口服营养补充3个月前后，使用KDQoL-SF™ 1.3测量了生活质量评分、肾脏疾病负担、三个生活质量量表以及心理和身体健康状况、营养状况的身体成分和生化参数。
患者的平均年龄为69.4±3.4岁，59%为男性，透析时间为63.5±52.6个月。将基线与透析期间口服营养补充的第3个月进行比较，我们观察到生活质量有所改善。与营养不良相反，评分，特别是与血液透析、性功能、社会和认知功能、睡眠、疼痛、能量/疲劳和总体健康状况相关的症状/问题清单评分显著增加。营养状况、能量摄入和身体成分指标也有显著变化。透析期间口服营养补充3个月后，我们观察到92%的患者在一个或多个指标上营养状况得到恢复。
我们的研究结果表明，3个月的透析期间口服营养补充可改善接受血液透析且被诊断为蛋白质能量丧失的老年患者的身心生活质量和营养状况。这些结果对于改善蛋白质能量丧失的血液透析患者的体验具有重要意义。
