不平等替代的故事：米诺环素与急性自身免疫性肝炎
A Tale of Unequal Substitution: Minocycline and Acute Autoimmune Hepatitis.
作者信息
Manning Dana H, DeBuck Emily, Simchick Mallory
机构信息
Wilkes University, Wilkes-Barre, PA, USA.
出版信息
J Pharm Technol. 2014 Apr;30(2):69-72. doi: 10.1177/8755122513520400. Epub 2014 Jan 10.
Abstract
In this case report, we describe the development of an acute autoimmune hepatitis associated with a short course of minocycline prescribed for a skin infection. Due to a drug shortage, minocycline was substituted for doxycycline. It is imperative that practitioners be aware of the different risks that accompany switching between drugs in the tetracycline class, particularly the risk of autoimmune conditions including hepatitis.
摘要
在本病例报告中，我们描述了一名因皮肤感染短期服用米诺环素后发生急性自身免疫性肝炎的病例。由于药物短缺，米诺环素被强力霉素替代。从业者必须意识到四环素类药物之间相互换药所伴随的不同风险，尤其是包括肝炎在内的自身免疫性疾病的风险。
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