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确定肺炎球菌结合疫苗(PCV13)接种的错失机会。

Identifying Missed Opportunities for the Pneumococcal Conjugate Vaccine (PCV13).

作者信息

Jindracek Lauren, Stark Jennifer E

机构信息

Washington Regional Medical Center, Fayetteville, AR, USA.

Veterans Health Care System of the Ozarks, Fayetteville, AR, USA.

出版信息

J Pharm Technol. 2018 Feb;34(1):24-27. doi: 10.1177/8755122517740364. Epub 2017 Nov 2.

DOI:10.1177/8755122517740364
PMID:34860987
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5998468/
Abstract

The recommendation for the pneumococcal conjugate vaccine (PCV13) in adults 65 years and older is recent, and the dosing schedule of PCV13 and the pneumococcal polysaccharide vaccine (PPSV23) can be complex in this population. The authors assessed the rate of PCV13 immunization in patients 65 years of age and older and identified barriers that contributed to missed opportunities for PCV13. This retrospective review evaluated outpatient Veterans age 65 years or older who did not receive PCV13 at a scheduled primary care appointment despite an electronic reminder. Investigators recorded any documented reason for the patient not receiving PCV13. The rate of PCV13 immunizations administered during the primary care visit study period was 37% (89 of 239 PCV13 eligible patients). Of the 150 patients identified who did not receive PCV13, 92% were not offered the vaccine, 6.7% declined vaccination, and 0.7% reported an allergy to vaccination. Electronic immunization records revealed that 48 of the 150 patients who did not receive PCV13 at their clinic appointment did receive PCV13 later the same year. Most patients received PCV13 in influenza vaccine season on the same day as receiving the influenza vaccine. The main barrier identified was not offering the vaccination during primary care visits. Pneumococcal vaccine administration was delayed until the influenza vaccine season in a significant portion of patients. This unexpected finding represents a target for education: ensuring health care professionals are reminded that PCV13 is not a seasonal vaccine like the influenza vaccine, but should be offered throughout the year.

摘要

65岁及以上成年人接种肺炎球菌结合疫苗(PCV13)的建议是最近才有的,在这一人群中,PCV13和肺炎球菌多糖疫苗(PPSV23)的接种程序可能很复杂。作者评估了65岁及以上患者中PCV13的免疫接种率,并确定了导致PCV13接种机会错失的障碍。这项回顾性研究评估了65岁及以上未在预定的初级保健预约中接种PCV13的门诊退伍军人,尽管有电子提醒。研究人员记录了患者未接种PCV13的任何书面原因。在初级保健就诊研究期间,PCV13的接种率为37%(239名符合PCV13接种条件的患者中有89名)。在确定的150名未接种PCV13的患者中,92%未被提供该疫苗,6.7%拒绝接种,0.7%报告对疫苗过敏。电子免疫记录显示,150名在诊所预约时未接种PCV13的患者中有48名在同年晚些时候接种了PCV13。大多数患者在流感疫苗接种季节与接种流感疫苗的同一天接种了PCV13。确定的主要障碍是在初级保健就诊时未提供疫苗接种。相当一部分患者的肺炎球菌疫苗接种被推迟到流感疫苗接种季节。这一意外发现是一个教育目标:确保提醒医疗保健专业人员,PCV13不像流感疫苗那样是季节性疫苗,而是应全年提供。

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J Pharm Technol. 2018 Feb;34(1):24-27. doi: 10.1177/8755122517740364. Epub 2017 Nov 2.
2
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本文引用的文献

1
Adult vaccination coverage--United States, 2010.成人疫苗接种覆盖率——美国,2010 年。
MMWR Morb Mortal Wkly Rep. 2012 Feb 3;61(4):66-72.
2
Healthcare utilization and cost of pneumococcal disease in the United States.美国肺炎球菌病的医疗利用和费用。
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3
Clinical and economic burden of pneumococcal disease in older US adults.美国老年人肺炎球菌病的临床和经济负担。
Vaccine. 2010 Jul 12;28(31):4955-60. doi: 10.1016/j.vaccine.2010.05.030. Epub 2010 May 22.
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Barriers to adult immunization.成人免疫接种的障碍。
Am J Med. 2008 Jul;121(7 Suppl 2):S28-35. doi: 10.1016/j.amjmed.2008.05.005.
5
Executive summary--Actions to strengthen adult and adolescent immunization coverage in the United States: policy principles of the Infectious Diseases Society of America.执行摘要——美国加强成人和青少年免疫接种覆盖率的行动:美国传染病学会的政策原则
Clin Infect Dis. 2007 Jun 15;44(12):1529-31. doi: 10.1086/519542. Epub 2007 May 14.