基于干细胞的胰岛细胞替代治疗糖尿病：一次抵达临床的旅行。
Stem cell-based islet replacement therapy in diabetes: A road trip that reached the clinic.
机构信息
Department of Internal Medicine, Leiden University Medical Center, P.O. Box 9600, 2300 RC, Leiden, the Netherlands; Transplantation Center, Leiden University Medical Center, P.O. Box 9600, 2300 RC, Leiden, the Netherlands.
Department of Internal Medicine, Leiden University Medical Center, P.O. Box 9600, 2300 RC, Leiden, the Netherlands.
出版信息
Cell Stem Cell. 2021 Dec 2;28(12):2044-2046. doi: 10.1016/j.stem.2021.11.008.
One hundred years after the discovery of insulin, Kieffer and colleagues (Ramzy et al., 2021) and Foyt and colleagues (Shapiro et al., 2021) report interim results from a multicenter clinical trial showing insulin secretion from engrafted pluripotent stem cell-derived endocrine progenitor cells in patients with type 1 diabetes.
胰岛素发现 100 年后，Kieffer 及其同事（Ramzy 等人，2021 年）和 Foyt 及其同事（Shapiro 等人，2021 年）报告了一项多中心临床试验的中期结果，该试验显示在 1 型糖尿病患者中，移植的多能干细胞衍生的内分泌祖细胞可分泌胰岛素。
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