富血小板纤维蛋白治疗麻风病营养性溃疡的疗效。
Efficacy of Platelet-Rich Fibrin in the Treatment of Trophic Ulcer in Leprosy.
机构信息
Department of Dermatology, Venereology and Leprology, Jawaharlal Nehru Medical College, Acharya Vinoba Bhave Rural Hospital, Wardha, Sawangi (Meghe), Wardha, Maharashtra, India.
Department of Dermatology, Venereology and Leprology, Jawaharlal Nehru Medical College, Acharya Vinoba Bhave Rural Hospital, Wardha, Sawangi (Meghe), Wardha, Maharashtra, India;
出版信息
Skinmed. 2021 Oct 1;19(5):362-368. eCollection 2021.
Trophic ulcer is a common disability in leprosy, recalcitrant to treatment. Platelet-rich fibrin (PRF) is a new technique for the treatment of trophic ulcer. A study was done to assess the efficacy of PRF in the treatment of trophic ulcer. Twenty-five patients of Wagner's Grade 2 trophic ulcer secondary to leprosy were enrolled. PRF was prepared and applied to ulcers and dressed; this was repeated weekly until complete healing or up to a maximum of six sittings. Ninety percent reduction in mean ulcer volume was seen at 6 weeks, with a mean healing time of 5 weeks. PRF is cost-effective, day care procedure with promising results in trophic ulcers.
营养性溃疡是麻风病的一种常见致残性疾病，且难以治疗。富含血小板纤维蛋白（PRF）是一种治疗营养性溃疡的新技术。本研究旨在评估 PRF 在治疗营养性溃疡中的疗效。共纳入 25 例麻风病导致的 Wagner 2 级营养性溃疡患者。制备 PRF 并应用于溃疡处敷贴，每周重复一次，直至完全愈合或最多进行 6 次治疗。6 周时，平均溃疡体积减少 90%，平均愈合时间为 5 周。PRF 是一种具有成本效益的日间护理程序，在治疗营养性溃疡方面具有良好的效果。
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