Departement of Surgery Pietro Valdoni, University Sapienza, Viale del Policlinico, 00100 Rome, Italy.
Department of Vascular and Endovascular Surgery, San Giovanni-Addolorata Hospital, Rome, Italy.
J Med Vasc. 2021 Oct-Dec;46(5-6):209-214. doi: 10.1016/j.jdmv.2021.07.002. Epub 2021 Aug 11.
Chemodectomas (CBTs) are the most frequently encountered tumours at the carotid bifurcation. Even if rare and commonly benign, their development close to the head and neck structures is often source of morbidity by compression and infiltration. Therefore, in order to avoid permanent neurologic or vascular complications these infrequent lesions need to be early removed. The total excision may be technically challenging and requires extensive expertise in surgical neck anatomy and a cooperative multidisciplinary approach. Almost a quarter of CBTs infiltrate carotid vessels so vascular expertise is pivotal in their resection. The present study aims to give an overview of vascular specificity and procedures required during surgical excision of such tumors to assist and guide treating physicians who encounter CBTs. This overview will particularly emphasize current therapeutic options: we discuss the referral criteria that should guide the decision about what type of preoperative care and surgical procedure should be offered to the affected patients. We also specify the epidemiologic data, screening recommendations and outcomes achieved with the different therapeutic approaches. The clinical, operative and follow-up data about a case of a Shamblin III carotid body tumour surgically removed by a multidisciplinary team at our Institution are also reported.
化学感受器瘤(CBT)是颈动脉分叉处最常见的肿瘤。即使罕见且通常为良性,但其靠近头颈部结构的发展常常因压迫和浸润而导致发病。因此,为了避免永久性的神经或血管并发症,这些罕见的病变需要早期切除。完全切除可能具有技术挑战性,需要在颈部解剖方面具有广泛的专业知识和多学科合作。几乎四分之一的 CBT 浸润颈动脉,因此血管专业知识对于其切除至关重要。本研究旨在概述此类肿瘤手术切除过程中的血管特异性和所需的程序,以协助和指导遇到 CBT 的治疗医生。本综述将特别强调当前的治疗选择:我们讨论了应指导决策的转诊标准,即应向受影响的患者提供哪种类型的术前护理和手术程序。我们还指定了不同治疗方法的流行病学数据、筛查建议和获得的结果。还报告了我们机构的多学科团队通过手术切除的 Shamblin III 型颈动脉体瘤的临床、手术和随访数据。