Health Management Center, Qingdao Chengyang District People's Hospital, Qingdao, China.
Endocrinology Department, Qingdao Chengyang District People's Hospital, Qingdao, China.
Pak J Pharm Sci. 2021 Sep;34(5(Special)):2065-2069.
To investigate the therapeutic effect of Danhong injection on diabetic patients with cerebral infarction and its influence on vascular endothelial function and hemodynamic level. A total of 100 diabetic patients with cerebral infarction admitted to our hospital from November 2019 to November 2020 were identified as the research subjects and randomly divided into a control group given routine treatment and a study group treated with Danhong injection, with 50 cases in each group. The efficiency of the two groups on vascular endothelial function, blood glucose level, National Institute of Health Stroke Scale (NIHSS) score, the incidence of adverse reactions, and hemodynamic indicators were compared. Most (98%) of patients in the study group displayed effective outcomes, which was significantly better than that in the control group. The study group outperformed the control study group in the vascular endothelial function, blood glucose level, NIHSS score and hemodynamic indicators (P<0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P>0.05). Danhong injection obtains a promising therapeutic effect on diabetic patients with cerebral infarction, as it significantly improves the vascular endothelial function and hemodynamic level.
探讨丹红注射液治疗糖尿病合并脑梗死患者的效果及其对血管内皮功能和血流动力学水平的影响。
选取 2019 年 11 月至 2020 年 11 月本院收治的 100 例糖尿病合并脑梗死患者作为研究对象，采用随机数字表法将其分为对照组和观察组，每组 50 例。对照组给予常规治疗，观察组在对照组基础上给予丹红注射液治疗。比较两组患者的血管内皮功能、血糖水平、美国国立卫生研究院卒中量表（NIHSS）评分、不良反应发生率及血流动力学指标。
观察组患者的治疗总有效率为 98.00%，显著高于对照组的 80.00%，差异有统计学意义（P<0.05）。观察组患者的血管内皮功能、血糖水平、NIHSS 评分及血流动力学指标均优于对照组，差异有统计学意义（P<0.05）。两组患者的不良反应发生率比较，差异无统计学意义（P>0.05）。
丹红注射液治疗糖尿病合并脑梗死患者的效果确切，可显著改善患者的血管内皮功能和血流动力学水平。
