Department of Orthopaedics, Shaanxi Provincial People's Hospital (third affiliated hospital of Xi'an jiaotong University), No. 256, Youyi West Road, Xi'an, China.
Shaanxi Provincial Key Laboratory of Infection and Immune Diseases, Shaanxi Provincial People's Hospital (third affiliated hospital of Xi'an jiaotong University), No. 256, Youyi West Road, Xi'an, China.
BMC Musculoskelet Disord. 2021 Dec 4;22(1):1013. doi: 10.1186/s12891-021-04889-z.
There is a paucity of data concerning the morphological differences of resected distal femurs and proximal tibias in osteoarthritic (OA) and normal knees. The objective of this study was to determine whether morphometric differences in the surfaces of resected distal femurs and proximal tibias exist between OA and normal knees in a Chinese population.
Ninety-four OA knees and ninety-five normal knees were evaluated in Chinese individuals. Computed tomography was used to measure the femoral mediolateral (fML), medial anteroposterior (fMAP), lateral anteroposterior (fLAP), medial condylar width (fMCW), lateral condylar width (fLCW), medial posterior condylar curvature radii (fMCR), lateral posterior condyle curvature radii (fLCR), fML/fMAP aspect ratio, tibial mediolateral (tML), middle anteroposterior (tAP), medial anteroposterior (tMAP), and lateral anteroposterior (tLAP) tML/tMAP aspect ratio to determine the morphologic differences between OA and normal knees.
The average fMCW and tMAP dimensions of OA knees were larger than those of normal knees in both male and female (p <0.05). The fMAP/fML aspect ratio and tMAP/tML aspect ratio were also significantly different in both sexs (p <0.05). OA knees have an oval-shaped distal femur with a wider ML length and more spherical-shaped proximal tibiae with relatively narrow ML dimensions.
The study revealed the morphological differences in fMCW, tMAP, fMAP/fML and tMAP/tML between OA and normal knees in both males and females. These findings may provide guidelines that can be used to design better knee implants that are more size-matched for OA knees.
关于骨关节炎（OA）和正常膝关节切除的远端股骨和近端胫骨的形态差异的数据很少。本研究的目的是确定在中国人中，OA 和正常膝关节之间切除的远端股骨和近端胫骨表面是否存在形态差异。
评估了 94 例 OA 膝关节和 95 例正常膝关节。使用计算机断层扫描测量股骨内外侧（fML）、内侧前后（fMAP）、外侧前后（fLAP）、内侧髁宽度（fMCW）、外侧髁宽度（fLCW）、内侧后髁曲率半径（fMCR）、外侧后髁曲率半径（fLCR）、fML/fMAP 纵横比、胫骨内外侧（tML）、中间前后（tAP）、内侧前后（tMAP）和外侧前后（tLAP）tML/tMAP 纵横比，以确定 OA 和正常膝关节之间的形态差异。
男性和女性 OA 膝关节的平均 fMCW 和 tMAP 尺寸均大于正常膝关节（p <0.05）。fMAP/fML 纵横比和 tMAP/tML 纵横比在两性中也有显著差异（p <0.05）。OA 膝关节的远端股骨呈椭圆形，ML 长度较宽，近端胫骨呈球形，ML 尺寸相对较窄。
该研究揭示了男性和女性 OA 和正常膝关节之间 fMCW、tMAP、fMAP/fML 和 tMAP/tML 的形态差异。这些发现可能为设计更符合 OA 膝关节尺寸的更好的膝关节植入物提供指导。
