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主客观睡眠差异对失眠认知行为疗法反应的影响。

Effects of subjective-objective sleep discrepancy on the response to cognitive behavior therapy for insomnia.

作者信息

Ahn Jun Seok, Bang Young Rong, Jeon Hong Jun, Yoon In-Young

机构信息

Department of Psychiatry, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Republic of Korea.

Department of Psychiatry, Dong-A University Hospital, Busan, Republic of Korea.

出版信息

J Psychosom Res. 2022 Jan;152:110682. doi: 10.1016/j.jpsychores.2021.110682. Epub 2021 Nov 22.

Abstract

OBJECTIVE

This study aimed to evaluate the clinical correlates of sleep discrepancy and how subjective-objective sleep discrepancy (SD) affects the results of cognitive behavioral therapy for insomnia (CBT-I) in patients with insomnia disorder.

METHODS

A total of 33 patients aged >55 years with insomnia disorders participated in this prospective cohort study. Sleep discrepancy (SD) was defined as the difference between the sleep duration derived from the PSG and self-report questionnaires. SD > 2 h was classified as high SD. Self-report questionnaires, and polysomnography (PSG) were performed before 4 weeks of group CBT-I. Statistical analyses were performed to investigate the association of SD with baseline characteristics and CBT-I results, and compare intergroup difference of pre and post-treatment of high SD and low SD.

RESULTS

Patients in the high SD group reported poor subjective sleep, such as lower sleep quality, shorter sleep duration, longer sleep latency, and lower sleep efficiency. However, they had longer sleep duration, higher sleep efficiency in the PSG. There were 35% males in low SD group, but no males in high SD group. After 4 weeks of group CBT-I, SD was positively associated with the effect of CBT-I on subjective total sleep time (r = 0.499, p < 0.006) and sleep efficiency (r = 0.463, p = 0.01) after adjusting age, sex and apnea-hypopnea index.

CONCLUSION

The results of this study suggest that patients in the high SD group may respond better to CBT-I than those in lower SD group. Evaluation of SD may help clinicians to decide tailored treatment strategies for treating insomnia disorders.

摘要

目的

本研究旨在评估睡眠差异的临床相关性,以及主观 - 客观睡眠差异(SD)如何影响失眠症患者的失眠认知行为疗法(CBT - I)效果。

方法

共有33名年龄大于55岁的失眠症患者参与了这项前瞻性队列研究。睡眠差异(SD)定义为多导睡眠图(PSG)得出的睡眠时间与自我报告问卷之间的差异。SD > 2小时被归类为高SD。在进行CBT - I组治疗前4周进行自我报告问卷和多导睡眠图(PSG)检查。进行统计分析以研究SD与基线特征及CBT - I结果的关联,并比较高SD组和低SD组治疗前后的组间差异。

结果

高SD组患者报告主观睡眠较差,如睡眠质量较低、睡眠时间较短、睡眠潜伏期较长和睡眠效率较低。然而,他们在PSG中的睡眠时间较长、睡眠效率较高。低SD组中有35%为男性,而高SD组中无男性。在CBT - I组治疗4周后,调整年龄、性别和呼吸暂停低通气指数后,SD与CBT - I对主观总睡眠时间的效果呈正相关(r = 0.499,p < 0.006)以及与睡眠效率呈正相关(r = 0.463,p = 0.01)。

结论

本研究结果表明,高SD组患者对CBT - I的反应可能优于低SD组患者。评估SD可能有助于临床医生为治疗失眠症制定个性化的治疗策略。

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