Department of Immunology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Department of Allergy and Clinical Immunology, Mofid Children's Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Int Arch Allergy Immunol. 2022;183(4):435-442. doi: 10.1159/000520510. Epub 2021 Dec 3.
The human microbiota plays a significant role in various mechanisms of the body. The formation of a healthy microbiota, especially in early childhood, has a significant effect on maintaining human health. Since the onset of coronavirus disease 2019 (COVID-19), the disease has caused many changes in human life. According to the available information, many of these factors affect the composition and diversity of the body's microbiota, so this pandemic may alter and disrupt the microbiota and consequently increase the incidence of other diseases such as allergic and autoimmune disorders, especially in children and infants born in this era. In this review, the probable impact of the COVID-19 pandemic on body's microbiota and its relationship with the emergence of future diseases is discussed.
人体微生物群在人体的各种机制中起着重要作用。健康微生物群的形成,尤其是在儿童早期,对维持人类健康有重要影响。自 2019 年冠状病毒病(COVID-19)爆发以来,这种疾病给人类生活带来了许多变化。根据现有资料,这些因素中的许多因素会影响人体微生物群的组成和多样性,因此这种大流行可能会改变和破坏微生物群,并由此增加其他疾病(如过敏性和自身免疫性疾病)的发病率,尤其是在这个时代出生的儿童和婴儿。在这篇综述中,讨论了 COVID-19 大流行对人体微生物群的可能影响及其与未来疾病出现的关系。