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在新冠疫情防控措施期间,慢性抗凝治疗管理出现脱节。单中心关于卡瓣机械瓣膜异常增加的经验。

Loss of engagement in controlling chronic anticoagulation therapy during Covid-19 stringency measures. A single center experience of disproportioned increase of stuck mechanical valves.

作者信息

Vriz Olga, Rossi Zadra Andrea, Eltayeb Abdalla, Asiri Fatima, Pragliola Claudio, Fawzy Nader, Galzerano Domenico, Feras Khalid, Alhalees Zohair, Kinsara Abdulhalim J, Elmula Fadl Elmula Mohamed Fadl

机构信息

Heart Centre Department, King Faisal Specialist Hospital and Research Center, Riyadh.

King Faisal Specialist Hospital & Research Centre .

出版信息

Monaldi Arch Chest Dis. 2021 Dec 3;92(2). doi: 10.4081/monaldi.2021.2065.

Abstract

Stuck valve is a very rare and severe complication that occurs in mechanical valve replacement patients with ineffective anticoagulation. However, with COVID-19 restriction measures, it became challenging to regularly assess INR to make sure it falls within the target therapeutic range to prevent this complication. We present a series of 10 patients who either underwent transthoracic echocardiography for a suspected stuck valve or were seen at the outpatient valve clinic with the residual consequences of a stuck valve during the COVID-19 restriction measures in our institute. Stuck prosthetic valves incident has increased significantly during this period, particularly those in the mitral position for which urgent replacement and prolonged hospitalization were necessary. Particularly with the COVID-19 restrictions in place, these cases highlight the need for physicians to be aware of the dramatic increase in the incidence of stuck prosthetic valves in patients on chronic warfarin therapy.

摘要

卡瓣是机械瓣膜置换术后抗凝效果不佳的患者中一种非常罕见且严重的并发症。然而,在新冠疫情防控措施下,定期评估国际标准化比值(INR)以确保其处于目标治疗范围内以预防该并发症变得具有挑战性。我们报告了10例患者,他们在我们研究所实施新冠疫情防控措施期间,因疑似卡瓣接受了经胸超声心动图检查,或在门诊瓣膜诊所因卡瓣的残留后果前来就诊。在此期间,人工瓣膜卡瓣事件显著增加,尤其是二尖瓣位置的卡瓣,这类情况需要紧急置换瓣膜并延长住院时间。特别是在实施新冠疫情防控措施的情况下,这些病例凸显了医生需要意识到接受长期华法林治疗的患者中人工瓣膜卡瓣发生率急剧上升的情况。

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