Sodeifian F, Mushtaq S, Rezaei N
Student Research Committee, School of Medicine, Shahid Beheshti University of Medical Science, Tehran, Iran.
Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), Tehran, Iran.
Actas Dermosifiliogr. 2021 Nov 27. doi: 10.1016/j.adengl.2021.11.033.
Coronavirus disease-19 (COVID-19) is an emerging health situation caused by the "severe acute respiratory syndrome coronavirus 2" (SARS-CoV-2). The ongoing COVID-19 pandemic which emerged from the Chinese city of Wuhan in December 2019 has spread to over 188 countries and infected over 100 million people across the globe in over one year. Most common symptoms of COVID-19 include fever and respiratory illness. Among extrapulmonary signs associated with COVID-19, dermatological manifestations have been increasingly reported from different geographical regions. The exact incidence or prevalence of COVID-19 associated skin manifestation remains largely unknown and the pathophysiological mechanisms are still unclear. In this article, we have attempted to give a comprehensive overview of what has been learned an year into the pandemic on the epidemiology, clinical and histopathological features, pathophysiological mechanisms and clinical management of COVID-19 associated cutaneous manifestations.
冠状病毒病-19（COVID-19）是由“严重急性呼吸综合征冠状病毒2”（SARS-CoV-2）引起的一种新出现的健康状况。2019年12月在中国武汉市出现的持续的COVID-19大流行，在一年多的时间里已蔓延至188多个国家，全球感染人数超过1亿。COVID-19的最常见症状包括发热和呼吸道疾病。在与COVID-19相关的肺外体征中，不同地理区域越来越多地报告了皮肤表现。与COVID-19相关的皮肤表现的确切发病率或患病率仍 largely unknown，其病理生理机制也仍不清楚。在本文中，我们试图对大流行一年来关于COVID-19相关皮肤表现的流行病学、临床和组织病理学特征、病理生理机制及临床管理方面所了解到的情况进行全面概述。
