新生儿期奈替米星治疗后的前庭毒性。
Vestibular toxicity following netilmicin therapy in the neonatal period.
作者信息
Hauch A M, Peitersen B, Peitersen E
出版信息
Dan Med Bull. 1986 Apr;33(2):107-9.
PMID:3486750
Abstract
Thirty-seven children treated with netilmicin during the neonatal period were seen at follow-up at the age of 2-4 years to investigate for possible vestibular damage caused by netilmicin therapy. No definite vestibular damage could be found in these 37 patients, including three patients in whom greatly elevated serum concentrations of netilmicin had been measured. The present study confirms previous findings in adults showing a low ototoxicity of netilmicin.
摘要
为了调查奈替米星治疗是否可能导致前庭损伤，对37名在新生儿期接受过奈替米星治疗的儿童进行了随访，随访时他们的年龄为2至4岁。在这37名患者中未发现明确的前庭损伤，其中包括三名血清奈替米星浓度大幅升高的患者。本研究证实了先前在成人中的研究结果，表明奈替米星的耳毒性较低。
相似文献
1
Vestibular toxicity following netilmicin therapy in the neonatal period.新生儿期奈替米星治疗后的前庭毒性。
Dan Med Bull. 1986 Apr;33(2):107-9.
2
Prospective evaluation of vestibular and auditory function in 76 patients treated with netilmicin.
Scand J Infect Dis Suppl. 1980;Suppl 23:122-5.
3
Netilmicin treatment followed by monitoring of vestibular and auditory function using highly sensitive methods.采用奈替米星治疗，随后使用高灵敏度方法监测前庭和听觉功能。
Scand J Infect Dis Suppl. 1980;Suppl 23:117-21.
4
5
Ototoxicity of netilmicin.
Acta Otolaryngol. 1982 Nov-Dec;94(5-6):421-9. doi: 10.3109/00016488209128930.
6
[Vestibular toxicity of gentamycin in newborn infants].[庆大霉素对新生儿的前庭毒性]
Laryngorhinootologie. 2001 Apr;80(4):173-6. doi: 10.1055/s-2001-13762.
7
Cisplatin vestibular ototoxicity: preliminary report.顺铂的前庭耳毒性：初步报告。
Laryngoscope. 1982 Dec;92(12):1363-8.
8
Intentional ablation of vestibular function using commercially available topical gentamicin-betamethasone eardrops in patients with Meniere's disease: further evidence for topical eardrop ototoxicity.在梅尼埃病患者中使用市售的局部用庆大霉素-倍他米松耳滴剂有意破坏前庭功能：局部耳滴剂耳毒性的进一步证据。
Laryngoscope. 2002 Apr;112(4):689-95. doi: 10.1097/00005537-200204000-00018.
9
Netilmicin in the treatment of neonates with moderate and severe infections.奈替米星治疗新生儿中重度感染
Scand J Infect Dis Suppl. 1980;Suppl 23:146-50.
引用本文的文献
1
Bayesian pharmacokinetic analysis of a gentamicin nomogram in neonates: a retrospective study.新生儿庆大霉素用药剂量图表的贝叶斯药代动力学分析：一项回顾性研究。
Curr Ther Res Clin Exp. 2003 Mar;64(3):178-88. doi: 10.1016/S0011-393X(03)00022-5.
2
Netilmicin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use.奈替米星。对其抗菌活性、药代动力学特性及治疗用途的综述。
Drugs. 1989 Nov;38(5):703-56. doi: 10.2165/00003495-198938050-00003.
Zotero 插件