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新生儿期奈替米星治疗后的前庭毒性。

Vestibular toxicity following netilmicin therapy in the neonatal period.

作者信息

Hauch A M, Peitersen B, Peitersen E

出版信息

Dan Med Bull. 1986 Apr;33(2):107-9.

PMID:3486750
Abstract

Thirty-seven children treated with netilmicin during the neonatal period were seen at follow-up at the age of 2-4 years to investigate for possible vestibular damage caused by netilmicin therapy. No definite vestibular damage could be found in these 37 patients, including three patients in whom greatly elevated serum concentrations of netilmicin had been measured. The present study confirms previous findings in adults showing a low ototoxicity of netilmicin.

摘要

为了调查奈替米星治疗是否可能导致前庭损伤,对37名在新生儿期接受过奈替米星治疗的儿童进行了随访,随访时他们的年龄为2至4岁。在这37名患者中未发现明确的前庭损伤,其中包括三名血清奈替米星浓度大幅升高的患者。本研究证实了先前在成人中的研究结果,表明奈替米星的耳毒性较低。

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