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巴基斯坦开伯尔-普赫图赫瓦省班努地区孕妇、非孕妇及5岁以下儿童疟疾的被动监测

Passive Surveillance of Malaria in Pregnant Women, Non-pregnant Women and Children Under 5 Years of Age in Bannu District, Khyber Pakhtunkhwa Pakistan.

作者信息

Qureshi Humera, Khan Muhammad Imran, Ahmad Akhlaq, Awan Usman Ayub, Khattak Aamer Ali, Khan Ayesha Ali, Sun Yaqiong

机构信息

Department of Mathematics and Statistics, The University of Haripur, Haripur, Pakistan.

Gungdong Provincial Key Laboratory of Allergy and Clinical Immunology, The State Key Laboratory of Respiratory Disease, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.

出版信息

Front Med (Lausanne). 2021 Nov 18;8:751456. doi: 10.3389/fmed.2021.751456. eCollection 2021.

Abstract

Malaria among pregnant women is one of the major causes of maternal and infant mortality and morbidity, especially in high-risk areas. Therefore, our study identified the burden of malaria for pregnant women, non-pregnant women, and children under 5 years of age, and malaria service health facilities in Bannu district, Khyber Pakhtunkhwa, Pakistan. A cross-sectional study was conducted. In this survey, 15,650 individuals were surveyed, and 1,283 were malaria-positive detected. The data were collected from 80 different healthcare centers. SPSS version 23 was used for data analysis. ArcGIS version 10.8 was used for study area mapping. Malaria was detected in 23.3% of children under five, 4.4% of pregnant women, and 72.3% of non-pregnant women, respectively. Moreover, , and mixed infection had a prevalence of 2.1, 96.8, and 1.1%. The most often used and effective medications to treat malaria were chloroquine (29.7%) and primaquine (69.4%). This study's findings depict that malaria's prevalence in the non-pregnant women's group was high. Additionally, infection was found to be more prevalent than other types of malaria infection. Due to the scarcity of healthcare facilities in this endemic region, special attention should be directed to strengthening the malaria surveillance and eradication programs.

摘要

孕妇疟疾是孕产妇和婴儿死亡及发病的主要原因之一,尤其是在高风险地区。因此,我们的研究确定了巴基斯坦开伯尔-普赫图赫瓦省班努地区孕妇、非孕妇和5岁以下儿童的疟疾负担,以及疟疾服务卫生设施情况。开展了一项横断面研究。在本次调查中,共对15650人进行了调查,检测出1283人疟疾呈阳性。数据来自80个不同的医疗保健中心。使用SPSS 23版进行数据分析。使用ArcGIS 10.8版绘制研究区域地图。五岁以下儿童、孕妇和非孕妇的疟疾检出率分别为23.3%、4.4%和72.3%。此外,混合感染的患病率分别为2.1%、96.8%和1.1%。治疗疟疾最常用且有效的药物是氯喹(29.7%)和伯氨喹(69.4%)。本研究结果表明,非孕妇群体中疟疾患病率较高。此外,发现该感染比其他类型的疟疾感染更为普遍。由于这一流行地区医疗设施匮乏,应特别关注加强疟疾监测和根除计划。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/564d/8636730/37da1a0fba8f/fmed-08-751456-g0001.jpg

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