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扁桃体切除术对小儿睡眠呼吸障碍患者肥胖的影响。

Impact of Tonsillectomy on Obesity in Pediatric Patients With Sleep-Disordered Breathing.

作者信息

Voora Rohith S, Carvalho Daniela, Jiang Wen

机构信息

School of Medicine, University of California, San Diego, San Diego, California, USA.

Pediatric Otolaryngology, Rady Children's Hospital San Diego, San Diego, California, USA.

出版信息

OTO Open. 2021 Nov 22;5(4):2473974X211059105. doi: 10.1177/2473974X211059105. eCollection 2021 Oct-Dec.

Abstract

OBJECTIVE

Both tonsillar hypertrophy and obesity contribute to pediatric sleep-disordered breathing (SDB). Tonsillectomy addresses anatomical obstruction causing SDB; however, it may adversely affect the obesity profile postoperatively. Herein, we investigate posttonsillectomy body mass index (BMI) changes in pediatric patients.

STUDY DESIGN

Retrospective case series.

SETTING

Tertiary, pediatric urban academic center.

METHODS

All patients undergoing tonsillectomy from January 1, 2016, to December 31, 2016, were included. Patients' age, sex, surgical indication, and preoperative BMI were recorded. Postoperative BMI data were collected between March 1, 2016, and December 31, 2017. Statistical analysis was performed using a generalized regression model, using BMI percentile-for-age weight status.

RESULTS

A total of 1153 patients were included (50% female), with age ranging from 2.0 to 19.5 years (mean [SD], 7.6 [4.0]). The majority (87.8%) had tonsillectomy for SDB. Of the cohort, 560 (48.6%) had available follow-up BMI data. The BMI percentile on the day of the surgery had a median of 65.8, and the BMI percentile on follow-up had a median of 76.4. The median time to follow-up was 197 days with a range of 50 to 605 days. Higher postoperative BMI percentile strongly correlated to higher preoperative BMI percentile ( < .001), as well as younger age ( < .001), male sex ( = .0005), and SDB as a surgical indication ( = .003).

CONCLUSION

We observed a significant increase in BMI percentile following tonsillectomy, which accounted for a significantly higher proportion of the cohort being classified as overweight or obese postoperatively. These findings necessitate greater preoperative counseling, closer follow-up, and adjunctive measures for obesity management in pediatric patients undergoing tonsillectomy.

摘要

目的

扁桃体肥大和肥胖均会导致小儿睡眠呼吸障碍(SDB)。扁桃体切除术可解决引起SDB的解剖学梗阻问题;然而,它可能会对术后的肥胖状况产生不利影响。在此,我们研究小儿患者扁桃体切除术后体重指数(BMI)的变化。

研究设计

回顾性病例系列研究。

研究地点

城市三级儿科学术中心。

方法

纳入2016年1月1日至2016年12月31日期间所有接受扁桃体切除术的患者。记录患者的年龄、性别、手术指征和术前BMI。术后BMI数据收集于2016年3月1日至2017年12月31日期间。采用广义回归模型进行统计分析,使用按年龄划分的BMI百分位数来评估体重状况。

结果

共纳入1153例患者(50%为女性),年龄范围为2.0至19.5岁(平均[标准差],7.6[4.0])。大多数患者(87.8%)因SDB接受扁桃体切除术。在该队列中,560例(48.6%)有可用的随访BMI数据。手术当天的BMI百分位数中位数为65.8,随访时的BMI百分位数中位数为76.4。随访的中位时间为197天,范围为50至605天。术后较高的BMI百分位数与术前较高的BMI百分位数密切相关(<0.001),也与年龄较小(<0.001)、男性(=0.0005)以及以SDB作为手术指征(=0.003)密切相关。

结论

我们观察到扁桃体切除术后BMI百分位数显著增加,这使得该队列中术后被归类为超重或肥胖的患者比例显著更高。这些发现需要在接受扁桃体切除术的小儿患者中进行更多的术前咨询、更密切的随访以及肥胖管理的辅助措施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/924c/8637722/44f910bd5c74/10.1177_2473974X211059105-fig1.jpg

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