SARS-CoV-2 感染率、检测率以及 HIV 感染者和非感染者中严重 COVID-19 结局。
SARS-CoV-2 incidence, testing rates, and severe COVID-19 outcomes among people with and without HIV.
机构信息
Division of HIV, ID, and Global Medicine.
Department of Epidemiology and Biostatistics.
出版信息
AIDS. 2021 Dec 1;35(15):2545-2547. doi: 10.1097/QAD.0000000000003075.
Abstract
To assess SARS-CoV-2 outcomes, we matched a municipal COVID-19 registry and clinic rosters from a municipal primary care network containing a large HIV clinic and assessed clinical outcomes by HIV status. The risk of severe COVID-19 was higher among people with HIV (PWH, adjusted relative risk = 1.84, 95% confidence interval = 1.05-3.25), while SARS-CoV-2 incidence was lower despite higher testing rates. SARS-CoV-2 vaccination campaigns should prioritize PWH to prevent severe COVID-19 disease given potentially higher risk.
摘要
为了评估 SARS-CoV-2 的结果，我们匹配了一个市级 COVID-19 注册中心和一个市级初级保健网络的诊所名单，该网络包含一个大型 HIV 诊所，并根据 HIV 状况评估了临床结果。HIV 感染者（PWH）发生重症 COVID-19 的风险更高（调整后的相对风险=1.84，95%置信区间=1.05-3.25），尽管检测率较高，但 SARS-CoV-2 的发病率却较低。鉴于潜在的更高风险，SARS-CoV-2 疫苗接种活动应优先考虑 HIV 感染者，以预防重症 COVID-19 疾病。
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