Nelson R W, Feldman E C
Vet Clin North Am Small Anim Pract. 1986 May;16(3):561-76. doi: 10.1016/s0195-5616(86)50061-9.
Pyometra is a relatively uncommon diestral uterine disorder seen primarily in older bitches and queens. The incidence of pyometra appears to be increasing, especially in younger animals, as a result of increasing use of estrogen and progesterone for mismating and for certain medical disorders. The clinical signs of pyometra and abnormalities on physical examination are dependent on the patency of the cervix and how quickly the client recognizes the problem. Ovariohysterectomy is still the treatment of choice; however, prostaglandin F2 alpha as a medical alternative in the management of pyometra is gaining more and more acceptance. The goal of prostaglandin F2 alpha therapy is to salvage the reproductive tract in the young breeding bitch or queen in the hopes of obtaining future litters. The results have been very promising, especially for bitches or queens with open-cervix pyometra. Prostaglandin F2 alpha appears to offer the owner a reasonable alternative in the management of pyometra.
子宫蓄脓是一种相对不常见的发情后期子宫疾病，主要见于老年母犬和母猫。由于越来越多地使用雌激素和孕酮来处理交配不当及某些疾病，子宫蓄脓的发病率似乎在上升，尤其是在较年轻的动物中。子宫蓄脓的临床症状和体格检查异常取决于子宫颈的通畅情况以及客户识别问题的速度。卵巢子宫切除术仍然是首选的治疗方法；然而，前列腺素F2α作为子宫蓄脓治疗的一种药物替代方法正越来越被接受。前列腺素F2α治疗的目标是挽救年轻繁殖母犬或母猫的生殖道，以期未来能产仔。结果非常有前景，尤其是对于子宫颈开放型子宫蓄脓的母犬或母猫。前列腺素F2α似乎为子宫蓄脓的管理为宠物主人提供了一个合理的替代选择。
