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[左旋咪唑治疗类风湿关节炎患者时的腺苷脱氨酶活性]

[Adenosine deaminase activity in levamisole treatment of patients with rheumatoid arthritis].

作者信息

Seidel W, Krüger W

出版信息

Z Gesamte Inn Med. 1986 Mar 15;41(6):172-4.

PMID:3487181
Abstract

Nine patients who fell ill with a classical or unequivocal rheumatoid arthritis were treated with 150 mg Levamisol a week. Before the beginning of the therapy and on the day after the fourth intake of medicaments the activity of the adenosine deaminase in lymphocytes, erythrocytes and in the plasma was determined. An influence on the enzyme activity by Levamisol could not be proved. Before as well as after the Levamisol therapy the enzyme activity in the erythrocytes was diminished.

摘要

9例患有典型或明确类风湿性关节炎的患者,每周接受150毫克左旋咪唑治疗。在治疗开始前以及第四次服药后的次日,测定淋巴细胞、红细胞及血浆中腺苷脱氨酶的活性。未证实左旋咪唑对酶活性有影响。在左旋咪唑治疗前后,红细胞中的酶活性均降低。

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