系统评价和荟萃分析骨盆修复联合抗应激性尿失禁手术治疗盆底功能障碍的疗效。

Systematic review and meta-analysis of therapeutic effects of pelvic restoration combined with anti-stress urinary incontinence surgery on pelvic floor dysfunction.

机构信息

Department of urology, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.

出版信息

Ann Palliat Med. 2021 Nov;10(11):11678-11687. doi: 10.21037/apm-21-2737.

DOI:10.21037/apm-21-2737

PMID:34872292

Abstract

BACKGROUND

In recent years, pelvic restoration surgery is widely used in the diagnosis and treatment of stress urinary incontinence (SUI) as people pay more attention to postpartum pelvic floor dysfunction (PFD). The therapeutic effect of pelvic restoration combined with anti-SUI surgery remains undetermined. The evaluation indicators of the therapeutic effects include the incidence of postoperative obstruction, the incidence of postoperative defecation difficulties, and the quality of life score.

METHODS

PubMed, Cochrane Library, and EMBASE were searched from the establishment of the database to April 2021 for randomized control trials (RCTs) of pelvic restoration and anti-SUI surgery, and the RevMan5.3 software provided by the Cochrane Collaboration was used for meta-analysis.

RESULTS

A total of 6 documents (a total of 1,944 patients) were included, including 1,021 patients in the experimental group and 923 patients in the control group. The incidence of obstruction after pelvic restoration combined with anti-SUI surgery was statistically significant (OR =1.35, 95% CI, 0.95-1.92, P=0.10); there was a statistically significant difference in the incidence of postoperative dyspareunia (OR =1.58, 95% CI, 0.91-2.74, P=0.10).

DISCUSSION

A total of 8 documents included in this meta-analysis confirmed that pelvic restoration combined with anti-SUI surgery for PFD can improve the prognosis and quality of life of patients.

摘要

背景

近年来，人们越来越关注产后盆底功能障碍（PFD），因此盆底修复术在压力性尿失禁（SUI）的诊断和治疗中得到了广泛应用。盆底修复联合抗 SUI 手术的治疗效果仍不确定。疗效评估指标包括术后梗阻发生率、术后排便困难发生率和生活质量评分。

方法

检索 PubMed、Cochrane Library 和 EMBASE 数据库，从建库至 2021 年 4 月，收集盆底修复联合抗 SUI 手术的随机对照试验（RCT），采用 Cochrane 协作网 RevMan5.3 软件进行 Meta 分析。

结果

共纳入 6 篇文献（共 1944 例患者），实验组 1021 例，对照组 923 例。盆底修复联合抗 SUI 手术后梗阻的发生率有统计学意义（OR=1.35，95%CI，0.95-1.92，P=0.10）；术后性交困难的发生率有统计学差异（OR=1.58，95%CI，0.91-2.74，P=0.10）。