Department of Plastic and Reconstructive Surgery, Norfolk and Norwich University Hospital NHS Foundation Trust, Norwich, UK; Norwich Medical School, University of East Anglia, Norwich, UK; Institute of Genetic Medicine, Newcastle University, Newcastle Upon Tyne, UK; Northumbria Healthcare NHS Foundation Trust, Tyne and Wear, UK.
Department of Plastic and Reconstructive Surgery, Norfolk and Norwich University Hospital NHS Foundation Trust, Norwich, UK; Department of Plastic Surgery and Burns, A.O.R.N A. Cardarelli Hospital, Naples, Italy.
J Plast Reconstr Aesthet Surg. 2022 Mar;75(3):1100-1107. doi: 10.1016/j.bjps.2021.09.043. Epub 2021 Oct 22.
When patients are unsuitable for deep inferior epigastric perforator (DIEP) flap breast reconstruction, the inferior gluteal artery perforator (IGAP) flap has been used as an alternative option. However, the profunda artery perforator (PAP) flap is also gaining popularity as an alternative to the DIEP flap for several reasons. This retrospective cohort study compares baseline characteristics, peri- and post-operative outcomes following IGAP flap and PAP flap breast reconstructions after mastectomy for cancer.
In a single center in the UK, from September 2008 through December 2016, 43 women underwent IGAP Flap(s) breast reconstruction and 51 received PAP flap(s) breast reconstructions. Statistical analysis was performed to compare baseline, peri-operative and post-operative variables between the two reconstruction methods.
Perioperative complications requiring reoperation were experienced in women undergoing IGAP flap breast reconstructions only (21% versus 0%, p = 0.001), principally due to the risk of total flap failure (12% versus 0%, p = 0.01). Women undergoing IGAP flap breast reconstructions were at significantly higher odds of revision surgery (OR 17 [95% CI: 5.5-53], p < 0.001), which was unchanged after adjusting for bilateral reconstructions (adjusted OR 18 [95% CI: 5.3-58], p < 0.001).
PAP flaps appear to be associated with significantly fewer complications and revision surgeries than IGAP flaps for breast reconstruction in women undergoing mastectomy for cancer and who are unsuitable for a DIEP flap breast reconstruction.
当患者不适合进行深部下腹壁穿支皮瓣(DIEP)乳房重建时,已将臀下动脉穿支皮瓣(IGAP)作为替代选择。但是,由于多种原因,深动脉穿支皮瓣(PAP)也越来越受欢迎,成为 DIEP 皮瓣的替代选择。本回顾性队列研究比较了因癌症而行乳房切除术的患者接受 IGAP 皮瓣和 PAP 皮瓣乳房重建后的基线特征、围手术期和术后结果。
在英国的一个单中心,2008 年 9 月至 2016 年 12 月,43 名女性接受了 IGAP 皮瓣乳房重建,51 名女性接受了 PAP 皮瓣乳房重建。对两种重建方法的基线、围手术期和术后变量进行了统计学分析。
仅接受 IGAP 皮瓣乳房重建的女性出现需要再次手术的围手术期并发症(21%与 0%,p=0.001),主要是由于总皮瓣失活的风险(12%与 0%,p=0.01)。接受 IGAP 皮瓣乳房重建的女性进行修复手术的可能性明显更高(OR 17 [95%CI:5.5-53],p<0.001),在调整双侧重建后仍然如此(调整后的 OR 18 [95%CI:5.3-58],p<0.001)。
对于因癌症而行乳房切除术且不适合 DIEP 皮瓣乳房重建的女性,PAP 皮瓣与 IGAP 皮瓣相比,乳房重建的并发症和修复手术明显更少。