Tirelli U, Vaccher E, Carbone A, De Paoli P, Morassut S
AIDS Res. 1986 Spring;2(2):149-53. doi: 10.1089/aid.1.1986.2.149.
Lymphangiography (LAG) and abdominal computed tomography (CT) were performed on 13 intravenous drug (heroin) abusers with persistent generalized lymphadenopathy (PGL). All 12 LAG performed were abnormal with a repetitive pattern of diffuse abnormalities of internal structures with small filling defects of both pelvic and abdominal lymph nodes. In 12/13 (92%) of the patients, lymphadenopathy was evidenced by CT scan as well. Retroperitoneal lymph nodes were always abnormal, mesenteric and pelvic nodes in 7 patients each. In 9/13 (69%) of the patients, the spleen was found to be moderately enlarged. The LAG films of our first 2 patients referred to us with an erroneous histologic diagnosis of malignant lymphoma were read to be consistent with involvement by lymphoma. Considering that patients with PGL are at risk for transformation to malignant lymphoma, the LAG and CT findings of PGL should be kept in mind when transformation to malignant lymphoma occurs and staging is performed.
对13例患有持续性全身淋巴结肿大（PGL）的静脉注射毒品（海洛因）滥用者进行了淋巴管造影（LAG）和腹部计算机断层扫描（CT）检查。所有12例进行的LAG检查均异常，表现为内部结构弥漫性异常的重复模式，盆腔和腹部淋巴结有小的充盈缺损。13例患者中有12例（92%）经CT扫描也证实有淋巴结肿大。腹膜后淋巴结总是异常，肠系膜和盆腔淋巴结各有7例异常。13例患者中有9例（69%）脾脏中度肿大。我们最初转诊来的2例组织学诊断错误为恶性淋巴瘤的患者，其LAG片经解读与淋巴瘤累及相符。鉴于PGL患者有转化为恶性淋巴瘤的风险，当发生向恶性淋巴瘤的转化并进行分期时，应牢记PGL的LAG和CT表现。
