Iuzbashian P G, Lvov A N, Tereshenko A V, Volel B A, Satrudinova R R, Romanov D V
Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.
Central State Medical Academy of Department of Presidential Affairs, Moscow, Russia.
Zh Nevrol Psikhiatr Im S S Korsakova. 2021;121(10):13-18. doi: 10.17116/jnevro202112110113.
To test the association between pain severity and anxiety, depression, and somatoform symptoms in burning sleep syndrome (BMS).
The study included 36 patients (33 women, 3 men), mean age 58.0±14.8 years. Psychopathological, clinical-dermatological, parametric, statistical methods were used. Psychometric examination included the Visual Analogue Scale (VAS) for assessment of pain (severity of glossalgia), PHQ-4 for self-assessment of severity of anxiety (GAD-2) and depression (PHQ-2), the Hospital Anxiety and Depression Scale (HADS), the Screening for Somatoform Symptoms-2 (SOMS-2), the Pittsburgh Sleep Quality Index (PSQI), the EQ-5D-5L quality of life assessment scale.
Insomnia in chronic pain is very common. On the one hand, studies show that sleep deprivation can enhance pain perception. On the other hand, chronic pain can trigger a variety of sleep disorders. One of the localizations of chronic pain syndrome is the oral mucosa. Somatoform pain disorder related to oral mucosa called «glossalgia» or «burning mouth syndrome» (BMS). The prevalence of insomnia in the study sample was 61.1%. The statistically significant positive correlation was found between the severity of insomnia (PSQI) and the severity of anxiety on both GAD-2 and HADS, while insomnia showed no correlation with depression and pain severity. At the same time, the severity of anxiety showed statistically significant positive correlation with the severity of pain assessed by VAS.
检验灼口综合征（BMS）中疼痛严重程度与焦虑、抑郁及躯体形式症状之间的关联。
该研究纳入了36例患者（33名女性，3名男性），平均年龄58.0±14.8岁。采用了心理病理学、临床皮肤病学、参数统计方法。心理测量检查包括用于评估疼痛（舌痛严重程度）的视觉模拟量表（VAS）、用于自评焦虑严重程度（广泛性焦虑障碍量表 - 2，GAD - 2）和抑郁严重程度（患者健康问卷 - 2，PHQ - 2）的患者健康问卷 - 4（PHQ - 4）、医院焦虑抑郁量表（HADS）、躯体形式症状筛查量表 - 2（SOMS - 2）、匹兹堡睡眠质量指数（PSQI）、EQ - 5D - 5L生活质量评估量表。
慢性疼痛中的失眠非常常见。一方面，研究表明睡眠剥夺会增强疼痛感知。另一方面，慢性疼痛会引发多种睡眠障碍。慢性疼痛综合征的发病部位之一是口腔黏膜。与口腔黏膜相关的躯体形式疼痛障碍称为“舌痛”或“灼口综合征”（BMS）。研究样本中失眠的患病率为61.1%。在失眠严重程度（PSQI）与GAD - 2和HADS上的焦虑严重程度之间发现了具有统计学意义的正相关，而失眠与抑郁及疼痛严重程度无相关性。同时，焦虑严重程度与VAS评估的疼痛严重程度之间存在具有统计学意义的正相关。
