Christensen W N, Long D M, Epstein J I
Hum Pathol. 1986 Jul;17(7):739-43. doi: 10.1016/s0046-8177(86)80184-8.
Cerebellopontine angle lipomas are rare lesions that differ from other intracranial lipomas in that they typically present with slowly progressive focal signs and symptoms identical to those of other tumors of this location, and by their propensity for intimate involvement of the adjacent cranial nerves. The lipomas in this study demonstrated this tendency to splay apart and infiltrate the cranial nerves, with the fatty tissue adjacent to the nerves invariably containing portions of the cranial nerves. Hence, the dissection of the adipose tissue from the nerves led to greater than anticipated postoperative neurologic deficits. Therefore, minimal excision of tumor is recommended to achieve decompression. Since preoperative evaluation does not distinguish with certainty this lesion from others more common to this location, intraoperative examination of frozen sections is required to confirm the diagnosis.
桥小脑角脂肪瘤是罕见的病变,与其他颅内脂肪瘤不同,它们通常表现为缓慢进展的局灶性体征和症状,与该部位的其他肿瘤相同,并且倾向于紧密累及相邻的颅神经。本研究中的脂肪瘤显示出这种向两侧分开并浸润颅神经的倾向,神经相邻的脂肪组织总是包含颅神经的部分。因此,从神经上剥离脂肪组织导致术后神经功能缺损比预期的要大。因此,建议尽量少切除肿瘤以实现减压。由于术前评估不能确定地将这种病变与该部位更常见的其他病变区分开来,因此需要术中检查冰冻切片以确诊。