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[阿根廷慢性透析患者中的新型冠状病毒肺炎感染情况]

[COVID-19 infection in chronic dialysis patients in Argentina].

作者信息

Bisigniano Liliana, Rosa-Diez Guillermo, Tagliafichi Viviana, Hansen-Krogh Daniela, Papaginovic Marina, Lombi Fernando, Soratti Carlos

机构信息

Instituto Nacional Central único Coordinador de Ablación e Implante (INCUCAI), Buenos Aires, Argentina.

Sociedad Argentina de Nefrología (SAN), Buenos Aires, Argentina. E-mail:

出版信息

Medicina (B Aires). 2021;81(6):916-921.

Abstract

The report of the preliminary data of the Argentine Registry of COVID in chronic dialysis is presented, from April 10, 2020 to April 9, 2021 and includes all dialysis centers in the country. In the study period, 36 918 prevalent patients on chronic dialysis were registered. COVID-19 infection was confirmed in 3709 patients (10% of prevalent patients), of which 1675 patients (45.2%) required hospitalization, and of these, 39% (550 patients) required ICU admission. 62% of those admitted to the ICU (339 patients) required mechanical ventilation (MV). 1307 patients died (35.24%). Multivariate analysis showed as factors associated with mortality from COVID in dialysis patients, age greater than 60 years (OR 2.6; 95% CI 2.2-3.1); diabetes (OR 1.5; 95% CI 1.3-1.8); time on dialysis greater than 55 months (OR 1.5; 95% CI 1.2-1.7); cerebrovascular disease (OR 1.6; 95% CI 1.1-2.3); neoplasia (OR 1.7; 95% CI 1.1-2.6); hospitalization requirement (OR 3.4; 95% CI 2.8-3.9); ICU admission (OR 1.8; 95% CI 1.3-2.5); need of MV (OR 11.8; 95% CI 6.9-20.2). The population on chronic dialysis in Argentina, as shown in the rest of the world, is highly vulnerable to COVID infection, showing a lethality 12 times higher than the general population. The measures implemented in dialysis units, patient care and their family environment, and above all priority vaccination are essential in this vulnerable population of patients.

摘要

本文呈现了阿根廷慢性透析患者新冠病毒感染情况登记处2020年4月10日至2021年4月9日的初步数据报告,涵盖了该国所有透析中心。在研究期间,共登记了36918例慢性透析患者。3709例患者(占现存患者的10%)确诊感染新冠病毒,其中1675例患者(45.2%)需要住院治疗,而这些患者中,39%(550例)需要入住重症监护病房(ICU)。入住ICU的患者中有62%(339例)需要机械通气(MV)。1307例患者死亡(35.24%)。多因素分析显示,与透析患者新冠病毒感染死亡率相关的因素包括:年龄大于60岁(比值比[OR]2.6;95%置信区间[CI]2.2 - 3.1);糖尿病(OR 1.5;95% CI 1.3 - 1.8);透析时间大于55个月(OR 1.5;95% CI 1.2 - 1.7);脑血管疾病(OR 1.6;95% CI 1.1 - 2.3);肿瘤(OR 1.7;95% CI 1.1 - 2.6);需要住院治疗(OR 3.4;95% CI 2.8 - 3.9);入住ICU(OR 1.8;95% CI 1.3 - 2.5);需要机械通气(OR 11.8;95% CI 6.9 - 20.2)。与世界其他地区情况一样,阿根廷的慢性透析患者群体极易感染新冠病毒,其死亡率比普通人群高出12倍。在透析单位、患者护理及其家庭环境中实施的措施,尤其是优先接种疫苗,对于这一脆弱的患者群体至关重要。

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