Nagasaka Takashi, Koitabashi Norimichi, Ishibashi Yohei, Aihara Kazufumi, Takama Noriaki, Ohyama Yoshiaki, Yokoyama Tomoyuki, Kaneko Yoshiaki
Department of Cardiovascular Medicine, Gunma University Graduate School of Medicine, Maebashi, Japan.
Department of Laboratory Sciences, Gunma University Graduate School of Health Sciences, Maebashi, Gunma, Japan.
J Cardiol Cases. 2022 May;25(5):285-288. doi: 10.1016/j.jccase.2021.11.006. Epub 2021 Dec 3.
Recently, new vaccine platforms-including mRNA vaccines for coronavirus disease 2019 (COVID-19) have been given emergency use authorization in Japan. Here, we present a rare case of myocarditis following a COVID-19 vaccine. In this case, myocarditis was confirmed by cardiac magnetic resonance imaging, endomyocardial biopsy, and troponin levels. The degree of myocardial inflammation in the endomyocardial biopsy samples was mild and the patient's clinical course was not severe. Although the pathology of myocarditis in this case was mild, further investigation would be needed. < Vaccination for coronavirus disease 2019 is advancing worldwide, but post-vaccination myocarditis is getting attention as a rare side effect. Although the myocarditis in this case was mild, the pathogenesis of the disease is unclear and needs to be thoroughly investigated in the vaccination.>.
最近，包括用于2019冠状病毒病（COVID-19）的mRNA疫苗在内的新型疫苗平台已在日本获得紧急使用授权。在此，我们报告一例COVID-19疫苗接种后发生心肌炎的罕见病例。在该病例中，通过心脏磁共振成像、心内膜活检和肌钙蛋白水平确诊为心肌炎。心内膜活检样本中的心肌炎症程度较轻，患者的临床病程并不严重。尽管该病例中心肌炎的病理表现较轻，但仍需进一步调查。<2019冠状病毒病疫苗接种正在全球范围内推进，但接种后心肌炎作为一种罕见的副作用正受到关注。尽管该病例中的心肌炎较轻，但该病的发病机制尚不清楚，需要在疫苗接种中进行深入研究。>
