Mahmoudvand Golnaz, Ebrahimzadeh Farzad, Mahmoudvand Behnaz, Tarhani Fariba
Student Research Committee, Lorestan University of Medical Sciences, Khorramabad, Iran.
Department of Biostatistics, School of Health and Nutrition, Lorestan University of Medical Sciences, Khorramabad, Iran.
Ann Med Surg (Lond). 2021 Nov 22;72:103093. doi: 10.1016/j.amsu.2021.103093. eCollection 2021 Dec.
Lumbar Puncture (LP) is a common invasive procedure where cerebrospinal fluid is obtained for the diagnosis of neurological anomalies. The purpose of this study was to evaluate the results of CSF analysis in patients admitted to pediatric wards.
In this retrospective descriptive study, records of the pediatric patients (aged <18 years) who were referred to our centers for lumbar puncture were evaluated. A checklist was prepared for all the patients where demographic data, findings of CSF and blood analysis and clinical presentations were recorded. The data obtained was analyzed using SPSSv22.
In this study a total number of 247 patients were included where 57.9% of the cases were of boys. 55.8% patients aged under 1 year and 62.3% of patients had a body temperature of 38 °C and above. 15.3% of the children were diagnosed with meningitis, 27.1% had febrile seizures, 9.3% had neonatal sepsis and for 48.2% cases other clinical diagnoses were made. There was a significant relationship between the diagnosis and the number of WBCs seen in CSF (P < 0.001). Also, there was a significant relationship between the diagnosis and amount of protein (P < 0.001) and glucose in CSF (P = 0.005). The age group and the type of fever and seizure were also significantly correlated, (P < 0.001).
Lumbar puncture is an important procedure for the diagnosis of several neurological diseases. Further studies including neuroimaging and therapeutic measures are recommended in this regard.
腰椎穿刺（LP）是一种常见的侵入性操作，通过获取脑脊液来诊断神经异常。本研究的目的是评估入住儿科病房患者的脑脊液分析结果。
在这项回顾性描述性研究中，对转诊至我们中心进行腰椎穿刺的儿科患者（年龄<18岁）的记录进行了评估。为所有患者准备了一份清单，记录人口统计学数据、脑脊液和血液分析结果以及临床表现。使用SPSSv22对获得的数据进行分析。
本研究共纳入247例患者，其中57.9%为男性。55.8%的患者年龄在1岁以下，62.3%的患者体温在38℃及以上。15.3%的儿童被诊断为脑膜炎，27.1%有热性惊厥，9.3%有新生儿败血症，48.2%的病例有其他临床诊断。诊断与脑脊液中白细胞数量之间存在显著关系（P<0.001）。此外，诊断与脑脊液中蛋白质含量（P<0.001）和葡萄糖含量（P=0.005）之间也存在显著关系。年龄组与发热和惊厥类型也显著相关（P<0.001）。
腰椎穿刺是诊断多种神经疾病的重要操作。在这方面，建议进一步开展包括神经影像学和治疗措施在内 的研究。
