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成人脊柱畸形矫正手术后唇疱疹复发

Reactivation of herpes simplex labialis following adult spine deformity correction surgery.

作者信息

Adsul Nitin, Hamim Idris, Banglore Mohan, Lee Robert

机构信息

Spine Deformity Unit, Royal National Orthopaedic Hospital, London, Stanmore, United Kingdom.

出版信息

Surg Neurol Int. 2021 Nov 16;12:562. doi: 10.25259/SNI_1042_2021. eCollection 2021.

Abstract

BACKGROUND

A depressed host defense is a major contributor to the oral shedding of herpes simplex virus (HSV) type 1. Here, we present an instance in which herpes simplex labialis was reactivated following major spinal deformity surgery.

CASE DESCRIPTION

A 59-year-old female underwent spinal deformity correction for lumbar degenerative scoliosis. On postoperative days 2-3, she presented with pyrexia (38°C) and tachycardia (94/min); by day 5 she had multiple ulcers around her lips and was HSV IgG positive. She had a remote history of herpes simplex I infection 7 years previously. Once started on oral acyclovir, the lesions improved, and by day 15 postoperative, her pyrexia and all lesions completely resolved.

CONCLUSION

HSV-1 should be suspected in patients with a previous history of HSV and postoperative pyrexia. Adequate prophylactic administration of acyclovir should result in resolution of these outbreaks, in this case, attributed to overly extensive spinal deformity surgery.

摘要

背景

宿主防御功能低下是1型单纯疱疹病毒(HSV)口腔脱落的主要原因。在此,我们介绍一例在脊柱严重畸形手术后唇疱疹复发的病例。

病例描述

一名59岁女性因腰椎退行性脊柱侧凸接受脊柱畸形矫正手术。术后第2 - 3天,她出现发热(38°C)和心动过速(94次/分钟);到第5天,她嘴唇周围出现多处溃疡,HSV IgG呈阳性。她7年前有过单纯疱疹I型感染史。一旦开始口服阿昔洛韦,病变有所改善,术后第15天,她的发热和所有病变完全消退。

结论

有HSV病史且术后发热的患者应怀疑感染HSV - 1。在本例中,由于脊柱畸形手术范围过大,充分预防性使用阿昔洛韦应能使这些疱疹发作得到缓解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a2a/8645498/72a8abd2f729/SNI-12-562-g001.jpg

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