Adsul Nitin, Hamim Idris, Banglore Mohan, Lee Robert
Spine Deformity Unit, Royal National Orthopaedic Hospital, London, Stanmore, United Kingdom.
Surg Neurol Int. 2021 Nov 16;12:562. doi: 10.25259/SNI_1042_2021. eCollection 2021.
A depressed host defense is a major contributor to the oral shedding of herpes simplex virus (HSV) type 1. Here, we present an instance in which herpes simplex labialis was reactivated following major spinal deformity surgery.
A 59-year-old female underwent spinal deformity correction for lumbar degenerative scoliosis. On postoperative days 2-3, she presented with pyrexia (38°C) and tachycardia (94/min); by day 5 she had multiple ulcers around her lips and was HSV IgG positive. She had a remote history of herpes simplex I infection 7 years previously. Once started on oral acyclovir, the lesions improved, and by day 15 postoperative, her pyrexia and all lesions completely resolved.
HSV-1 should be suspected in patients with a previous history of HSV and postoperative pyrexia. Adequate prophylactic administration of acyclovir should result in resolution of these outbreaks, in this case, attributed to overly extensive spinal deformity surgery.
宿主防御功能低下是1型单纯疱疹病毒(HSV)口腔脱落的主要原因。在此,我们介绍一例在脊柱严重畸形手术后唇疱疹复发的病例。
一名59岁女性因腰椎退行性脊柱侧凸接受脊柱畸形矫正手术。术后第2 - 3天,她出现发热(38°C)和心动过速(94次/分钟);到第5天,她嘴唇周围出现多处溃疡,HSV IgG呈阳性。她7年前有过单纯疱疹I型感染史。一旦开始口服阿昔洛韦,病变有所改善,术后第15天,她的发热和所有病变完全消退。
有HSV病史且术后发热的患者应怀疑感染HSV - 1。在本例中,由于脊柱畸形手术范围过大,充分预防性使用阿昔洛韦应能使这些疱疹发作得到缓解。