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Hydrogen-Deuterium Exchange Mass Spectrometry (HDX-MS) Centroid Data Measured between 3.6 °C and 25.4 °C for the Fab Fragment of NISTmAb.在3.6°C至25.4°C之间测量的NIST单克隆抗体Fab片段的氢-氘交换质谱（HDX-MS）质心数据。
J Res Natl Inst Stand Technol. 2019 May 2;124:1-7. doi: 10.6028/jres.124.009. eCollection 2019.
2
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Hydrogen/deuterium exchange mass spectrometry with improved electrochemical reduction enables comprehensive epitope mapping of a therapeutic antibody to the cysteine-knot containing vascular endothelial growth factor.氢/氘交换质谱结合改良电化学还原法实现了含半胱氨酸结的血管内皮生长因子治疗性抗体的全面表位作图。
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Probing Protein-Membrane Interactions and Dynamics Using Hydrogen-Deuterium Exchange Mass Spectrometry (HDX-MS).利用氢氘交换质谱法（HDX-MS）探测蛋白质-膜相互作用和动态。
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Interlaboratory Studies Using the NISTmAb to Advance Biopharmaceutical Structural Analytics.利用美国国家标准与技术研究院单克隆抗体推进生物制药结构分析的实验室间研究
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Hydrogen-Deuterium Exchange Mass Spectrometry: A Novel Structural Biology Approach to Structure, Dynamics and Interactions of Proteins and Their Complexes.氢-氘交换质谱法：一种研究蛋白质及其复合物的结构、动力学和相互作用的新型结构生物学方法。
Life (Basel). 2020 Nov 15;10(11):286. doi: 10.3390/life10110286.

本文引用的文献

1
Interlaboratory Comparison of Hydrogen-Deuterium Exchange Mass Spectrometry Measurements of the Fab Fragment of NISTmAb.NISTmAb 抗体 Fab 片段的氢氘交换质谱测量的实验室间比较
Anal Chem. 2019 Jun 4;91(11):7336-7345. doi: 10.1021/acs.analchem.9b01100. Epub 2019 May 14.
2
Data on crystal organization in the structure of the Fab fragment from the NIST reference antibody, RM 8671.来自美国国家标准与技术研究院（NIST）参考抗体RM 8671的Fab片段结构中的晶体组织数据。
Data Brief. 2017 Nov 8;16:29-36. doi: 10.1016/j.dib.2017.11.013. eCollection 2018 Feb.
3
Biophysical characterization and structure of the Fab fragment from the NIST reference antibody, RM 8671.美国国家标准与技术研究院（NIST）参考抗体RM 8671的Fab片段的生物物理特性及结构
Biologicals. 2017 Nov;50:27-34. doi: 10.1016/j.biologicals.2017.09.005. Epub 2017 Sep 29.
4
Analytical Aspects of Hydrogen Exchange Mass Spectrometry.氢交换质谱分析法的分析方面
Annu Rev Anal Chem (Palo Alto Calif). 2015;8:127-48. doi: 10.1146/annurev-anchem-062011-143113. Epub 2015 May 29.
5
Simultaneous reduction and digestion of proteins with disulfide bonds for hydrogen/deuterium exchange monitored by mass spectrometry.用质谱法监测含二硫键的蛋白质的同时还原和酶解进行氢/氘交换。
Anal Chem. 2010 Feb 15;82(4):1450-4. doi: 10.1021/ac902550n.
6
A universal algorithm for fast and automated charge state deconvolution of electrospray mass-to-charge ratio spectra.一种用于电喷雾质荷比谱快速自动电荷态去卷积的通用算法。
J Am Soc Mass Spectrom. 1998 Mar;9(3):225-33. doi: 10.1016/S1044-0305(97)00284-5.
7
Primary structure effects on peptide group hydrogen exchange.肽基团氢交换的一级结构效应
Proteins. 1993 Sep;17(1):75-86. doi: 10.1002/prot.340170110.

Hydrogen-Deuterium Exchange Mass Spectrometry (HDX-MS) Centroid Data Measured between 3.6 °C and 25.4 °C for the Fab Fragment of NISTmAb.

作者信息

Hudgens Jeffrey W, Gallagher Elyssia S, Karageorgos Ioannis, Anderson Kyle W, Huang Richard Y-C, Chen Guodong, Bou-Assaf George M, Espada Alfonso, Chalmers Michael J, Harguindey Eduardo, Zhang Hui-Min, Walters Benjamin T, Zhang Jennifer, Venable John, Steckler Caitlin, Park Inhee, Brock Ansgar, Lu Xiaojun, Pandey Ratnesh, Chandramohan Arun, Anand Ganesh Srinivasan, Nirudodhi Sasidhar N, Sperry Justin B, Rouse Jason C, Carroll James A, Rand Kasper D, Leurs Ulrike, Weis David D, Al-Naqshabandi Mohammed A, Hageman Tyler S, Deredge Daniel, Wintrode Patrick L, Papanastasiou Malvina, Lambris John D, Li Sheng, Urata Sarah

机构信息

National Institute of Standards and Technology, Bioprocess Measurement Group, Biomolecular Measurements Division, Gaithersburg, MD 20899, USA.

Institute for Bioscience and Biotechnology Research, 9600 Gudelsky Drive, Rockville, MD 20850, USA.

出版信息

J Res Natl Inst Stand Technol. 2019 May 2;124:1-7. doi: 10.6028/jres.124.009. eCollection 2019.

DOI:10.6028/jres.124.009
PMID:34877153
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7339623/
Abstract
摘要